Evidence map›Paper›PMID 40796809›Full record

ArticleBMC geriatrics2025

The incidence of sensorineural hearing loss diagnoses in people with and without Alzheimer's disease - a nationwide cohort study.

Kaisa Hokkinen, Aarno Dietz, Pasi Lampela, Sirpa Hartikainen, Anna-Maija Tolppanen

Abstract read
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Article in BMC geriatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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0cells of the map it votes in
3citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kaisa HokkinenKuopio Research Centre of Geriatric Care, School of Pharmacy, University of Eastern Finland, University of Eastern Finland, Yliopistonranta 1, Kuopio, 70210, Finland. kaisas@student.uef.fi.
Aarno DietzDepartment of Otorhinolaryngology, Kuopio University Hospital, Kuopio, Finland.
Pasi LampelaKuopio Research Centre of Geriatric Care, School of Pharmacy, University of Eastern Finland, University of Eastern Finland, Yliopistonranta 1, Kuopio, 70210, Finland.
Sirpa HartikainenKuopio Research Centre of Geriatric Care, School of Pharmacy, University of Eastern Finland, University of Eastern Finland, Yliopistonranta 1, Kuopio, 70210, Finland.
Anna-Maija TolppanenKuopio Research Centre of Geriatric Care, School of Pharmacy, University of Eastern Finland, University of Eastern Finland, Yliopistonranta 1, Kuopio, 70210, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSensorineural hearing loss (SNHL) is a risk factor for cognitive impairment, but little is known on whether the diagnosis of Alzheimer's disease (AD) affects the diagnosis of SNHL. We studied the temporal changes in the incidence of SNHL diagnosis in relation to AD diagnosis.

methodsThis study is part of Medicine use and Alzheimer's disease cohort (MEDALZ) study. Our nationwide register-based study included 42,934 community-dwelling persons who received a clinically verified AD diagnosis in 2008-2011 in Finland and a 1:1 matched comparison cohort. We calculated the incidence of SNHL diagnoses per 100 person-years (PY) from ten years before to five years after the date of AD diagnosis (index date).

resultsBefore the index date, the incidence of SNHL diagnoses was higher among persons with AD (1.51/100 PY) than in the comparison cohort (1.34/100 PY, adjusted hazard ratio, 95%Cl 1.10, 1.06-1.13). After AD diagnosis the incidence was lower among persons with AD (1.05 and 1.66/100 PY, adjusted hazard ratio, 95%Cl 0.60, 0.56-0.62). The incidence increased in a similar manner in both groups before the AD diagnosis. In the AD group the incidence peaked at the index date, but steeply declined shortly after, while in the comparison cohort, it continued its previous ascending course.

conclusionsThe incidence of SNHL diagnosis declines after AD diagnosis, suggesting that AD may alter diagnostic trajectories and access to audiological care.

Indexed as

Alzheimer DiseaseHearing Loss, SensorineuralAgedAged, 80 and overCohort StudiesFemaleFinlandHumansIncidenceMaleMiddle AgedRegistriesCognitive impairmentHearing lossHearing rehabilitation

Identifiers

PMID40796809
PMCPMC12341112

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.