Evidence map›Paper›PMID 40796803›Full record

ArticleBMC geriatrics2025

Association of sensory and motor impairments with dementia: a cross-sectional analysis in US older adults.

Anis Davoudi, Yuri Agrawal, Hang Wang, Ryan J Dougherty, Amal A Wanigatunga, Nicholas S Reed, Joshua R Ehrlich, Alden L Gross, Jennifer A Schrack

Abstract read
In one paragraph

Article in BMC geriatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Anis DavoudiJohns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA. adavoud3@jh.edu.
Yuri AgrawalSchool of Medicine, University of Colorado, Aurora, CO, USA.
Hang WangJohns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
Ryan J DoughertyDepartment of Kinesiology & Health, Rutgers University, New Brunswick, NJ, USA.
Amal A WanigatungaJohns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
Nicholas S ReedJohns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
Joshua R EhrlichDepartment of Ophthalmology and Visual Sciences, University of Michigan Medical School, Ann Arbor, MI, USA.
Alden L GrossJohns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
Jennifer A SchrackJohns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.

Funding

The National Health and Trends StudyU01AG032947 · NIA · JOHNS HOPKINS UNIVERSITY · PI VICKI A. FREEDMAN, JENNIFER ANN SCHRACK · 2008 to 2026
$169.4M
Research Education ComponentP30AG066507 · NIA · JOHNS HOPKINS UNIVERSITY · PI Corinne Pettigrew · 2020 to 2026
$29.3M
Research Education CoreP30AG024824 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Lona Mody, RAYMOND L YUNG · 2004 to 2026
$29.2M
Preclinical AD ConsortiumRF1AG059869 · NIA · JOHNS HOPKINS UNIVERSITY · PI ALBERT, MARILYN S. · 2018 to 2018
$7.7M
Socioeconomic, Cardiovascular, and Psychosocial Sources of Cross-National Variation in Cognitive Health Among Older AdultsR01AG070953 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Alden L. Gross, Lindsay C Kobayashi · 2021 to 2026
$4.6M
Contribution of sensorimotor function to risk and pathogenic mechanisms of Alzheimer's disease and related dementiasR01AG061786 · NIA · JOHNS HOPKINS UNIVERSITY · PI AGRAWAL, YURI, LIN, FRANK R · 2019 to 2023
$3.7M
Vision Impairment in the National Health and Aging Trends StudyR01EY034479 · NEI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Joshua Robert Ehrlich · 2023 to 2026
$2.6M
The Role of Hearing Loss in Health Care Outcomes.K23AG065443 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI REED, NICHOLAS SALVATORE · 2020 to 2024
$943k
Energy expenditure, cognitive function, and biomarker features of Alzheimer's diseaseK01AG080122 · NIA · RUTGERS, THE STATE UNIV OF N.J. · PI Ryan James Dougherty · 2023 to 2026
$501k
NIA NIH HHS K01 AG080122NIA NIH HHS K23 AG065443NIA NIH HHS P30 AG024824NIA NIH HHS P30 AG066507NIA NIH HHS R01AG061786NIA NIH HHS R01AG070953NIA NIH HHS U01AG032947NIH HHS K01AG080122NIH HHS R01EY034479NIH HHS RF1AG059869
6 · The paper itself

Abstract

backgroundImpairments in sensory and motor function are common in older adults and have been linked with higher prevalence of dementia. However, their independent associations with dementia have not been examined in a nationally representative population.

methodsCross-sectional analysis of the National Health and Aging Trends Study (NHATS; Round 11/2021) of U.S. Medicare beneficiaries. Dementia was classified per NHATS protocol as none, possible, or probable dementia. Vision measures included presenting binocular distance visual acuity, near visual acuity, and contrast sensitivity. Hearing measures included the pure tone average of the better ear. Motor function measures included gait speed, chair stands time, balance score, and grip strength. Dichotomized or categorized presence of impairment in each sensory and motor function was defined and used as the main exposures. Multivariable survey-weighted logistic regression was used to assess the independent associations of sensory and motor function impairments with dementia status.

resultsOur final analytic sample included 2,379 participants with 36.6% aged

conclusionsFindings suggest current impairment in vision or motor function may be strong indicators of prevalent dementia in older adults.

Indexed as

DementiaSensation DisordersVision DisordersAgedAged, 80 and overCross-Sectional StudiesFemaleHumansMaleUnited States

Identifiers

PMID40796803
PMCPMC12341113

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.