Evidence map›Paper›PMID 40796800›Full record

Observational studyBMC medical imaging2025

Anatomical features of aortic root in patients with aortic stenosis treated by TAVR: an observational study.

Yang Chen, Baihua Sun, Zhongyu Wang, Moyang Wang, Hongliang Zhang, Guannan Niu, Zhenyan Zhao, Dejing Feng, Pinghai Zhang, Zhibo Jiang and 3 more

Abstract readObservational Study
In one paragraph

Observational study in BMC medical imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Escalating Diameter Buddy Balloon in Transcatheter Aortic Valve Implantation With Complex Aortic Arch.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yang Chen *Coronary Heart Disease Center, National Center for Cardiovascular Diseases and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China.
Baihua Sun *Department of Radiology, Linyi People's Hospital, Linyi, Shandong, 250013, China.
Zhongyu Wang *Department of Medicine, Qingdao University, Qingdao, Shandong, 266071, China.
Moyang WangCoronary Heart Disease Center, National Center for Cardiovascular Diseases and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China.
Hongliang ZhangCoronary Heart Disease Center, National Center for Cardiovascular Diseases and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China.
Guannan NiuCoronary Heart Disease Center, National Center for Cardiovascular Diseases and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China.
Zhenyan ZhaoCoronary Heart Disease Center, National Center for Cardiovascular Diseases and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China.
Dejing FengCoronary Heart Disease Center, National Center for Cardiovascular Diseases and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China.
Pinghai ZhangShanghai MicroPort CardioFlow Medtech Co., Ltd, Shanghai, 200090, China.
Zhibo JiangShanghai MicroPort CardioFlow Medtech Co., Ltd, Shanghai, 200090, China.
Junhua Yuan *Department of Special Medicine, School of Basic Medicine, Qingdao University, Qingdao, Shandong, 266021, China. yuanjunhua322@126.com.ORCID 0000-0002-6829-2359
Junxian Song *Department of Cardiology, Peking University People's Hospital, Beijing, 100044, China. jx221@163.com.
Yongjian Wu *Coronary Heart Disease Center, National Center for Cardiovascular Diseases and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China. wuyongjian@fuwai.com.ORCID 0000-0002-5590-8396

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTranscatheter aortic valve replacement (TAVR) is a well-established technique for the treatment of aortic stenosis (AS). However, due to the complex anatomical features of the aortic root, the risk of vascular injury caused by operation under the condition of anatomical variations of the aortic root is high, and there is a lack of studies on the anatomical features of the aortic root on CT before TAVR. Therefore, this study will preliminarily summarize anatomical features of aortic root in patients with aortic stenosis treated by TAVR.

methodsA retrospective study was conducted at a single center, involving 60 patients with symptomatic severe AS treated TAVR between September 2022 and December 2022. Baseline patient information, CT measurements of aortic root anatomical characteristics, and associated risks were analyzed.

resultsThe mean age of the 60 patients was 77.72 ± 4.33 years, with 39 males (65.00%). The left ventricular ejection fraction was 65.46 ± 13.92%. Valve morphology included 38 cases (63.30%) of tricuspid valves and 22 cases (36.70%) of bicuspid valves. Common anatomical risks identified were acute aortic arch (18.33%), a short ascending aorta (10.00%, 8.33%, 16.67%, 15.00%), ascending aortic dilation (3.33%), a transverse heart (28.33%), cardiac anteversion (68.33%), a short left ventricle (5.00%), and a small left ventricle (5.00%).

conclusionPreoperative cardiac CT scans detect aortic root morphological angle abnormalities in TAVR patients. Angular dimensions of the aortic root show considerable variability among patients, which may have procedural implications for TAVR.

Indexed as

AortaAortic ValveAortic Valve StenosisTranscatheter Aortic Valve ReplacementAgedAged, 80 and overFemaleHumansMaleRetrospective StudiesTomography, X-Ray ComputedAortic root characteristicsAortic valve stenosisTranscatheter aortic valve replacement

Identifiers

PMID40796800
PMCPMC12341228

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.