Trial reportScientific reports2025
Comparative outcomes of penile skin grafts versus buccal mucosal grafts in urethroplasty for the treatment of extensive anterior urethral strictures.
Trial report in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Penile skin graft versus buccal mucosal graft for anterior urethral strictures in adult urethroplasty- a systematic review and meta-analysis.International urology and nephrology · 2026Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To compare the outcomes of augmentation urethroplasty (AU) performed with either buccal mucosa graft (BMG) or penile skin graft (PSG) in managing long-segment anterior urethral strictures. A prospective randomized trial involved 98 patients diagnosed with anterior urethral stricture scheduled to AU between June 2022 and December 2024. Participants were randomly assigned to either the PSG or BMG arms. The comparison included patient demographics, clinicopathological characteristics of strictures, and surgical outcomes. The primary outcome was the success rate at 12 months. Secondary outcomes included functional parameters, such as the Urethral Stricture Surgery-Patient Related Outcome Measure (USS-PROM), the International Prostate Symptom Score (IPSS), the International Index of Erectile Function (IIEF) Score, the Male Sexual Health Questionnaire for Ejaculatory Dysfunction (MSHQ-EJD), Q-max, and perioperative complications. The study arms were comparable regarding the preoperative parameters with a mean stricture length ± SD of 6.4 ± 2.3 and 7.9 ± 4.1 cm for PSG and BMG, respectively (p = 0.11). After a median follow-up of 20 months (12-30), the success rates of AU with PSG and BMG were comparable (93.2% v/s 97.9%, respectively; p = 0.346). There was no statistically significant difference in the IIEF (p = 0.8) and MSHQ-EJD (p = 0.22). The improvements in USS-PROM: LUTS domain (p = 0.19), USS-PROM: peeling voiding score (p = 0.62), IPSS (p = 0.43), and Q-max (p = 0.39) were comparable between the study arms. Clavien-Dindo grade I-III complications were 6.8 and 8.3% (p = 0.8), with patients' satisfaction of 90.9% and 93.8% (p = 0.5) for PSG and BMG, respectively. Kaplan-Meier survival analysis showed no statistically significant difference in stricture-free survival among both techniques (hazard ratio 1.19; p = 0.275). Our study demonstrates that PSG and BMG techniques for augmentation anterior urethroplasty have high and comparable success rates, with equal patient satisfaction and similarly low morbidity. Neither technique negatively affected sexual or ejaculatory functions.
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