ArticleScientific reports2025
Functionalization of gelatin films dressings with silver-doped zinc oxide nanoparticles for prevention of bacterial infection and promoting wound repair.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Data-Driven Engineering of Antimicrobial Nanomaterials for Food Safety and Biomedical Systems.Nanomaterials (Basel, Switzerland) · 2026Review
- Comprehensive Characterization of Solution-Cast Polycaprolactone/MXene/Gelatin Composite Films for Biomedical Applications.Biopolymers · 2026Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gelatin-based films loaded with silver-doped zinc oxide nanoparticles (Ag-doped ZnONPs) were synthesized using the solution casting technique. The analyzed data of Ag-doped ZnONPs reveal their spherical shape with a small size. In our work, three different concentrations of the prepared Ag-doped ZnONPs (0.05 g, 0.1 g, and 0.2 g) were added to GeL solution for the formation of three films (Ag/ZnO 0.05@GeL film, Ag/ZnO 0.1@GeL film, and Ag/ZnO 0.2@GeL). These prepared films were compared with GeL film that prepared without Ag-ZnONPs. The obtained results demonstrated the relatively homogeneous distribution of Ag-ZnONPs on the surface of the prepared films. Besides, this study investigated the antibacterial properties, biocompatibility, and potential applications of Ag/ZnO 0.2@GeL film for wound healing. Ag/ZnO 0.2@GeL film exhibited the highest antibacterial efficacy, with zones of inhibition ranging from 17 to 21 mm against Gram-negative bacteria. Furthermore, this formulation showed a marked ability to inhibit biofilm formation, completely eradicating bacterial biofilm by day 7. In bacterial growth inhibition assays, Ag/ZnO 0.2@GeL reduced bacterial counts by up to 6 log CFU/mL within 210 min. Biocompatibility was assessed using a Microtox® analyzer, with EC
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