Evidence map›Paper›PMID 40796691›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2025

Investigation of instrumentation lengthening in the thoracolumbar junction of the spine - an in vitro Biomechanical study.

Bastian Welke, Michael Schwarze, Christof Hurschler, Shadi Kedah, Dorothea Daentzer, Dennis Nebel

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Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Bastian WelkeHannover Medical School, Department of Orthopaedic Surgery, Laboratory for Biomechanics and Biomaterials, Hannover Medical School, Department of Orthopaedic Surgery, Laboratory for Biomechanics and Biomaterials, Germany. welke.bastian@mh-hannover.de.
Michael SchwarzeHannover Medical School, Department of Orthopaedic Surgery, Laboratory for Biomechanics and Biomaterials, Hannover Medical School, Department of Orthopaedic Surgery, Laboratory for Biomechanics and Biomaterials, Germany.
Christof HurschlerHannover Medical School, Department of Orthopaedic Surgery, Laboratory for Biomechanics and Biomaterials, Hannover Medical School, Department of Orthopaedic Surgery, Laboratory for Biomechanics and Biomaterials, Germany.
Shadi KedahHannover Medical School, DIAKOVERE Annastift, Department of Orthopaedic Surgery, Spine Section, Hannover Medical School, DIAKOVERE Annastift, Department of Orthopaedic Surgery, Spine Section, Germany.
Dorothea DaentzerHannover Medical School, DIAKOVERE Annastift, Department of Orthopaedic Surgery, Spine Section, Hannover Medical School, DIAKOVERE Annastift, Department of Orthopaedic Surgery, Spine Section, Germany.
Dennis NebelHannover Medical School, Department of Orthopaedic Surgery, Laboratory for Biomechanics and Biomaterials, Hannover Medical School, Department of Orthopaedic Surgery, Laboratory for Biomechanics and Biomaterials, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeInstrumented posterior lumbar fixation (PLF) with fusion is the surgical standard for treating various degenerative changes or deformities of the spine. Several studies have shown the risk of adjacent segment pathology following fusion. Therefore, revision procedures are often required which involve extension of instrumentation to adjacent levels. The purpose of this study was to evaluate the stability of multisegmental-instrumentation of the lumbar spine when extended with continuous rods or with connectors to the lower mid thoracic spine.

methodsEight human specimens from Th5 to S1 were used and loaded with moments of 7.5 Nm about the three anatomical axes. A total of eight different PLF configurations were examined, with three conditions in a short Th10-S1 instrumentation and five conditions with a long Th6-S1 instrumentation. Continuous rods, and axial and lateral connectors were used to extend the PLF. Total range of motion (tROM) and total neutral zone (tNZ), as well as the intersegmental range of motion (iROM), were evaluated.

resultsOverall, all configurations of the PLF demonstrated high primary stability. The iROM was less than 2 degrees in all segments studied where lengthening was performed with continuous rods or connectors. We found only a few significant differences, which are unlikely to be clinically relevant due to their very small magnitudes.

conclusionFrom a biomechanical point of view, the axial and lateral connectors provide comparable primary stability to a continuous rod system. Thus, the use of connectors is likely to be a suitable approach of extending an existing lumbar fixation to the lower and mid thoracic spine. LEVEL OF EVIDENCE: Biomechanical study.

Indexed as

Internal FixatorsLumbar VertebraeSpinal FusionThoracic VertebraeAgedBiomechanical PhenomenaCadaverFemaleHumansMaleMiddle AgedRange of Motion, ArticularConnectorIn vitro biomechanicsPosterior lumbar fixationRod systemSpinal fixationThoracolumbar spine

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.