Evidence map›Paper›PMID 40796568›Full record

ArticleNPJ Parkinson's disease2025

Remote real time digital monitoring fills a critical gap in the management of Parkinson's disease.

Aarushi S Negi, Shreesh Karjagi, Laura Parisi, Kerry W Daley, Annie K Abay, Aryaman S Gala, Kevin B Wilkins, Shannon L Hoffman, Margaret S Ferris, Hengameh Zahed and 3 more

Abstract read
In one paragraph

Article in NPJ Parkinson's disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Aarushi S Negi *Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
Shreesh Karjagi *Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
Laura ParisiDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
Kerry W DaleyDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
Annie K AbayDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
Aryaman S GalaDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
Kevin B WilkinsDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
Shannon L HoffmanDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
Margaret S FerrisDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
Hengameh ZahedDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
Gaurav M ChattreeDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
Bianca PalushajDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
Helen M Bronte-StewartDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA. hbs@stanford.edu.

Funding

Bilateral Closed Loop Deep Brain Stimulation for Freezing of Gait using Neural and Kinematic FeedbackUH3NS107709 · NINDS · STANFORD UNIVERSITY · PI BRONTE-STEWART, HELEN · 2019 to 2023
$6.1M
Neurostimulation of the Nucleus Basalis of Meynert for the Cognitive-Motor Syndrome in Parkinson's DiseaseUH3NS128150 · NINDS · STANFORD UNIVERSITY · PI Helen Bronte-Stewart · 2024 to 2026
$3.6M
NINDS NIH HHS UH3 NS107709NINDS NIH HHS UH3 NS128150
6 · The paper itself

Abstract

People with Parkinson's disease (PWP) face significant gaps in care. Limited neurologist access, infrequent clinic visits, and inadequate symptom measurement culminate in suboptimal therapy and high morbidity. Quantitative Digitography (QDG) provides validated, digital metrics of the three cardinal motor signs in Parkinson's disease (PD) in real-time from 30 seconds of a mobility task on a digitography device and can be used remotely or in clinical settings. This study demonstrates the feasibility and clinical relevance of 30-day remote QDG monitoring. Participants showed excellent compliance and found the system easy to use. The QDG Mobility Score demonstrated meaningful correlation with Activities of Daily Living (ADLs), captured motor complexities across a broad PD duration, and tracked motor changes from small therapy adjustments. QDG offers providers and PWP an accessible, objective, and real-time tool to remotely monitor motor symptoms, optimize treatment, and address care gaps created by infrequent clinic visits and subjective symptom assessment.

Identifiers

PMID40796568
PMCPMC12344058

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.