Evidence map›Paper›PMID 40796548›Full record

ArticleNature communications2025

Sustainable DNA-polysaccharide hydrogels as recyclable bioplastics.

Yujie Ke, Kai Lan, Jing Yi Wong, Hongfang Lu, Shujun Gao, Keunhyuk Ryu, Feng Chen, Wei Wei Loh, Zhili Dong, Jason Y C Lim and 4 more

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Yujie Ke *Institute of Materials Research and Engineering (IMRE), Agency for Science, Technology and Research (A*STAR), 2 Fusionopolis Way, Innovis #08-03, Singapore, 138634, Republic of Singapore.
Kai Lan *Department of Forest Biomaterials, North Carolina State University, 2820 Faucette Drive, Raleigh, North Carolina, 27695, USA.ORCID http://orcid.org/0000-0002-4622-6326
Jing Yi WongInstitute of Materials Research and Engineering (IMRE), Agency for Science, Technology and Research (A*STAR), 2 Fusionopolis Way, Innovis #08-03, Singapore, 138634, Republic of Singapore.
Hongfang LuInstitute of Materials Research and Engineering (IMRE), Agency for Science, Technology and Research (A*STAR), 2 Fusionopolis Way, Innovis #08-03, Singapore, 138634, Republic of Singapore.
Shujun GaoNational Neuroscience Institute, 11 Jln Tan Tock Seng, Singapore, 308433, Republic of Singapore.
Keunhyuk RyuSchool of Materials Science and Engineering, Nanyang Technological University, Singapore, 639798, Republic of Singapore.ORCID http://orcid.org/0000-0003-2934-5371
Feng ChenInstitute of Materials Research and Engineering (IMRE), Agency for Science, Technology and Research (A*STAR), 2 Fusionopolis Way, Innovis #08-03, Singapore, 138634, Republic of Singapore.
Wei Wei LohInstitute of Materials Research and Engineering (IMRE), Agency for Science, Technology and Research (A*STAR), 2 Fusionopolis Way, Innovis #08-03, Singapore, 138634, Republic of Singapore.
Zhili DongSchool of Materials Science and Engineering, Nanyang Technological University, Singapore, 639798, Republic of Singapore.ORCID http://orcid.org/0000-0001-8116-6747
Jason Y C LimInstitute of Materials Research and Engineering (IMRE), Agency for Science, Technology and Research (A*STAR), 2 Fusionopolis Way, Innovis #08-03, Singapore, 138634, Republic of Singapore.ORCID http://orcid.org/0000-0002-8020-1720
Zhaogang DongInstitute of Materials Research and Engineering (IMRE), Agency for Science, Technology and Research (A*STAR), 2 Fusionopolis Way, Innovis #08-03, Singapore, 138634, Republic of Singapore.ORCID http://orcid.org/0000-0002-0929-7723
Xi ChenSchool of Interdisciplinary Studies, Lingnan University, Tuen Mun, Hong Kong SAR, China. chenxi@ln.edu.hk.ORCID http://orcid.org/0000-0002-8911-4172
Itamar WillnerInstitute of Chemistry, The Center for Nanoscience and Nanotechnology, The Hebrew University of Jerusalem, Jerusalem, 91904, Israel. itamar.willner@mail.huji.ac.il.ORCID http://orcid.org/0000-0001-9710-9077
Yuwei HuInstitute of Materials Research and Engineering (IMRE), Agency for Science, Technology and Research (A*STAR), 2 Fusionopolis Way, Innovis #08-03, Singapore, 138634, Republic of Singapore. ywhu@imre.a-star.edu.sg.ORCID http://orcid.org/0000-0002-7282-4143

Funding

Agency for Science, Technology and Research (A*STAR) C210112014A*STAR | Science and Engineering Research Council (Science and Engineering Research Council - A STAR) KIMR220901aSERCRF
6 · The paper itself

Abstract

Traditional petrochemical-derived plastics are challenging to recycle and degrade, and the existing (re)process methods are organic solvent-based and/or energy-intensive, resulting in significant environmental contamination and greenhouse gas emissions. This study presents a sustainable bioplastic material characterized by multi-closed-loop recyclability and water (re)processability. The bioplastics are derived from abundant polysaccharide sources of dextran, alginic acid, carboxymethyl cellulose, and DNA of plant and living organism waste. The process involves chemical oxidation of polysaccharides to produce aldehyde-functionalized derivatives, which subsequently form reversible imine covalent bonds with amine groups in DNA. This reaction yields water-processable polysaccharide/DNA crosslinked hydrogels, serving as raw materials for producing sustainable bioplastics. The bioplastic products exhibit (bio)degradability and recyclability, enabling aqueous recovery of the hydrogel constituents through plastic hydrolysis and the natural biodegradability of DNA and polysaccharides. These products demonstrate excellent resistance to organic solvents, self-healing, scalability, and effective processing down to nanometer scales, underscoring their potential for broad and versatile applications. The work provides potential pathways for advancing sustainable and environmentally friendly bioplastic materials.

Indexed as

Biodegradable PlasticsDNAHydrogelsPlasticsPolysaccharidesRecyclingAlginatesHydrolysisAlginatesBiodegradable PlasticsDNAHydrogelsPlasticsPolysaccharides

Identifiers

PMID40796548
PMCPMC12344013

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.