ReviewEuropean heart journal2025
Myocardial compression and recoil as determinants of coronary blood flow.
Review in European heart journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Association of endothelial glycocalyx degradation with post-PCI slow flow phenomenon in STEMI patients: a prospective observational study.Cardiovascular diagnosis and therapy · 2026Article
- An Automated Modular Platform for Vascular Graft Assessment via Coronary-like Flow-Induced Stimulation.Bioengineering (Basel, Switzerland) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Coronary blood flow is conventionally analysed as a continuous flow of blood through a tube with the input of energy in the epicardial coronary arteries and the principal resistance to flow in the arterioles and the small arteries. This model has been studied in detail and is accepted by all expert groups. However, this essay argues that this model is valid but incomplete. Coronary blood flow is not continuous. Coronary blood flow is phasic and asynchronous. During systole, at rest, there is no forward flow to the left ventricle in the epicardial coronary arteries. But there is forward flow in systole in the coronary veins. The blood forced during systole into the coronary veins is expelled from the coronary microcirculation by myocardial contraction and represents the compressible volume of the coronary microcirculation. During diastole, inflow of blood from the epicardial coronary artery begins abruptly, accelerated by myocardial recoil, refilling the compressible volume of the coronary microcirculation, and then flowing through the coronary vein. Accordingly, the hydrostatic energy in the epicardial coronary artery is not the only energy propelling blood through the coronary circulation. Myocardial compression and recoil also contribute. Disorders of myocardial compression and myocardial recoil in diastole should be considered in the differential diagnosis of disorders of the microcirculation. Thus, reduced coronary flow reserve in heart failure with preserved ejection fraction might be a consequence, rather than a cause, of myocardial dysfunction.
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