ArticleAmerican journal of epidemiology2026
Lack of relationship between posttraumatic stress disorder and coronary atherosclerotic burden among twin veterans from the Vietnam era.
Article in American journal of epidemiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
Post-traumatic stress disorder (PTSD) has been related to ischemic heart disease (IHD), and the primary substrate for IHD is atherosclerotic burden. We aim to estimate the association between exposure to PTSD and atherosclerotic burden in PTSD-discordant twin pairs. This is a cross-sectional examination of 212 male twins during the 2016-2019 study visit of the Vietnam Era Twin Registry. Current PTSD symptom severity was assessed with the Clinician-Administered PTSD Scale for DSM-IV. PTSD-discordant twins were defined as pairs with different values of the PTSD Symptoms Scale. We regressed the log-transformed CAC Score on the PTSD Scale adjusted for potential confounders using linear mixed models and reported exponentiated coefficients. The sample had a median age of 68 (IQR67-70) years, a 15% prevalence of PTSD (median Symptom Score of 61; IQR53-81), and a median CAC Score of 111 (IQR5-346). The median CAC Score was 69 (IQR0.40-229) in twins with higher PTSD symptoms and 89 (IQR6.6-243) in their brothers with lower PTSD symptoms. The model estimated a -0.95% difference in CAC Score per unit increment in PTSD Symptoms Score within pairs (95%CI -2.6%;+0.7%), not implying a relationship between PTSD and coronary atherosclerosis in a design that inherently controls for familial and early environmental factors.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.