Evidence map›Paper›PMID 40795341›Full record

ArticleJournal of Korean medical science2025

Sun Ha Choi, Jin Eun Choi, Mi Jeong Hong, Jang Hyuck Lee, Hyo-Gyoung Kang, Sook Kyung Do, Won Kee Lee, Ji Eun Park, Yong Hoon Lee, Hyewon Seo and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of Korean medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Sun Ha Choi *Cell and Matrix Research Institute, School of Medicine, Kyungpook National University, Daegu, Korea.ORCID https://orcid.org/0000-0002-9665-7466
Jin Eun Choi *Cell and Matrix Research Institute, School of Medicine, Kyungpook National University, Daegu, Korea.ORCID https://orcid.org/0000-0001-7833-2257
Mi Jeong HongCell and Matrix Research Institute, School of Medicine, Kyungpook National University, Daegu, Korea.ORCID https://orcid.org/0000-0002-9504-334X
Jang Hyuck LeeCell and Matrix Research Institute, School of Medicine, Kyungpook National University, Daegu, Korea.ORCID https://orcid.org/0000-0001-5537-3013
Hyo-Gyoung KangCell and Matrix Research Institute, School of Medicine, Kyungpook National University, Daegu, Korea.ORCID https://orcid.org/0000-0003-0600-227X
Sook Kyung DoCell and Matrix Research Institute, School of Medicine, Kyungpook National University, Daegu, Korea.ORCID https://orcid.org/0000-0002-3829-3828
Won Kee LeeBiostatistics, Medical Research Collaboration Center in Kyungpook National University Hospital and School of Medicine, Kyungpook National University, Daegu, Korea.ORCID https://orcid.org/0000-0003-4217-5792
Ji Eun ParkDepartment of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Korea.ORCID https://orcid.org/0000-0002-4202-3126
Yong Hoon LeeDepartment of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Korea.ORCID https://orcid.org/0000-0001-5972-2866
Hyewon SeoDepartment of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Korea.ORCID https://orcid.org/0000-0003-0533-8863
Jaehee LeeDepartment of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Korea.ORCID https://orcid.org/0000-0001-8111-7320
Shin Yup LeeCell and Matrix Research Institute, School of Medicine, Kyungpook National University, Daegu, Korea.ORCID https://orcid.org/0000-0002-2121-7335
Seung Ick ChaDepartment of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Korea.ORCID https://orcid.org/0000-0002-7246-0909
Chang Ho KimDepartment of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Korea.ORCID https://orcid.org/0000-0002-1550-5752
Jae Yong ParkCell and Matrix Research Institute, School of Medicine, Kyungpook National University, Daegu, Korea.ORCID https://orcid.org/0000-0001-7993-4495
Seung Soo YooCell and Matrix Research Institute, School of Medicine, Kyungpook National University, Daegu, Korea.ORCID https://orcid.org/0000-0002-7309-9254

Funding

Kyungpook National University
6 · The paper itself

Abstract

backgroundEpidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) are the standard first-line treatment for patients with advanced lung cancer harboring activating

methodsWe enrolled 266 patients with advanced lung cancer treated with EGFR-TKIs and examined 30 putative functional polymorphisms across 11 genes involved in the EGFR signaling pathway. Associations between these polymorphisms and clinical outcomes were assessed.

resultsAmong the polymorphisms analyzed,

conclusionThe

Indexed as

Lung NeoplasmsProtein Kinase InhibitorsProto-Oncogene Proteins c-aktA549 CellsAdultAgedAllelesAntineoplastic AgentsCell Line, TumorErbB ReceptorsFemaleGenotypeHumansMaleMiddle AgedMutationAKT1 protein, humanAntineoplastic AgentsEGFR protein, humanErbB ReceptorsProtein Kinase InhibitorsProto-Oncogene Proteins c-aktAKT1 PolymorphismChemotherapy ResponseEGFR-TKINon-Small Cell Lung CancerProgression-Free Survival

Identifiers

PMID40795341
PMCPMC12339898

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.