Evidence map›Paper›PMID 40795339›Full record

ArticleJournal of Korean medical science2025

Impact of

Jaekyung Bae, Eun Young Park, Uisuk Kim, Junhwan Kim, Ji Hyun Kim, June Young Chun, Young Ju Choi, Myong Cheol Lim

Abstract read
In one paragraph

Article in Journal of Korean medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Medicina (Kaunas, Lithuania) · 2025
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jaekyung BaeCenter for Gynecologic Cancer, National Cancer Center, Goyang, Korea.ORCID https://orcid.org/0009-0006-1699-4662
Eun Young ParkBiostatistics Collaboration Team, Research Institute, National Cancer Center, Goyang, Korea.ORCID https://orcid.org/0000-0003-2430-5282
Uisuk KimCenter for Gynecologic Cancer, National Cancer Center, Goyang, Korea.ORCID https://orcid.org/0000-0002-1279-3701
Junhwan KimCenter for Gynecologic Cancer, National Cancer Center, Goyang, Korea.ORCID https://orcid.org/0000-0001-6807-1233
Ji Hyun KimCenter for Gynecologic Cancer, National Cancer Center, Goyang, Korea.ORCID https://orcid.org/0000-0002-4746-5572
June Young ChunDepartment of Internal Medicine, National Cancer Center, Goyang, Korea.ORCID https://orcid.org/0000-0001-9345-6645
Young Ju ChoiDepartment of Internal Medicine, National Cancer Center, Goyang, Korea.ORCID https://orcid.org/0000-0001-6530-5612
Myong Cheol LimCenter for Gynecologic Cancer, National Cancer Center, Goyang, Korea.ORCID https://orcid.org/0000-0001-8964-7158

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo investigate the impact of

methodsThis retrospective study included patients with primary ovarian cancer diagnosed with CDI at the National Cancer Center, Korea, between January 2014 and December 2023. Patients with gastrointestinal symptoms and positive

resultsA total of 111 CDI episodes were identified in 90 patients, with 17 patients experiencing recurrent CDI. Among initial CDI episodes, 51.1% occurred during the first or second cycle of adjuvant chemotherapy after cytoreductive surgery. Adjuvant chemotherapy cycles were delayed in 81.1% of cases, with a median delay of 13 days. Additionally, 7.8% of patients discontinued chemotherapy, and CDI-related mortality was 2.2%. Severe or fulminant CDI was associated with higher rates of intensive care unit admission, bowel surgery, or death (38.9% vs. 4.2%;

conclusionCDI can cause chemotherapy delays and severe adverse outcomes, such as septic shock or death. Early identification of CDI and a multidisciplinary approach are essential to minimize CDI-related complications in patients with ovarian cancer. Further research is needed to develop preventive strategies and evaluate the long-term impact of CDI on cancer prognosis.

Indexed as

Clostridioides difficileClostridium InfectionsOvarian NeoplasmsShock, SepticAdultAgedAnti-Bacterial AgentsAntineoplastic Combined Chemotherapy ProtocolsChemotherapy, AdjuvantCytoreduction Surgical ProceduresFemaleHospitalizationHospital MortalityHumansIntensive Care UnitsMiddle AgedAnti-Bacterial AgentsChemotherapyClostridium difficileOvarian Cancer

Identifiers

PMID40795339
PMCPMC12339900

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.