ArticleAesthetic surgery journal2025
Prepectoral Breast Reconstruction: Early and Long-Term Complications and Outcomes of Total Coverage Acellular Dermal Matrix and Implants Vs Polyurethane-Coated Implants Without Use of Acellular Dermal Matrix.
Article in Aesthetic surgery journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Reconstructing Aesthetics: Aesthetic Surgery Journal and Aesthetic Breast Reconstruction.Aesthetic surgery journal · 2026Article
- Changing Paradigms in Polyurethane-coated Breast Implant Surgery: A Bibliometric Analysis of 4 Decades of Clinical Practice.Plastic and reconstructive surgery. Global open · 2026Article
- Capsular Contracture in Implant-Based Breast Reconstruction: A Comprehensive Narrative Review of Pathophysiology, Risk Factors, and Contemporary Controversies.Medicina (Kaunas, Lithuania) · 2026Review
- Pre-Pectoral Polyurethane Implant Reconstruction Following Batwing Skin-Reducing Mastectomy: A Single-Center Study.Journal of clinical medicine · 2026Article
- Bibliometric analysis of the top 100 most-cited articles on tissue expander use in breast reconstruction: insights from CiteSpace, VOSviewer, and Bibliometrix.Gland surgery · 2025Article
- Post-Mastectomy Direct-to-Implant Pre-Pectoral Breast Reconstruction With Polyurethane-Coated Implants: A Systematic Review of Efficacy and Safety.Aesthetic surgery journal. Open forum · 2025Review
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundImmediate prepectoral breast reconstruction has emerged as a prominent alternative to subpectoral techniques, offering favorable outcomes in selected patients. Among available options, implant coverage with acellular dermal matrix (ADM) and the use of polyurethane (PU)-coated implants without ADM represent 2 widely adopted strategies.
objectivesThe aim of the authors this study is to examine the comparative efficacy and complication profiles of implant coverage with ADM and the use of PU-coated implants without ADM.
methodsThis retrospective cohort study included 97 patients (135 breasts) undergoing immediate prepectoral breast reconstruction following nipple-sparing, skin-sparing, or skin-reducing mastectomy between April 2015 and October 2019. Patients were stratified into 2 groups: those receiving ADM-covered textured implants and those receiving PU-coated implants. Outcomes assessed included early (<4 weeks), mid-term (>4 weeks), and long-term (≥1 year) complications, as well as aesthetic results evaluated through blinded assessment using a standardized Likert scale.
resultsPU-coated implants were associated with significantly lower rates of early postoperative seroma (2.9% vs 33.8%, P < .001) and infection (1.4% vs 6.2%). At 5 years, the incidence of severe capsular contracture (Baker Grade 3-4) was markedly higher in the ADM group (47.7% vs 24.3%, P < .001), particularly in patients who had not received postmastectomy radiotherapy. No significant differences were observed in the incidence of rippling or step-off deformities. Aesthetic outcomes were superior in the PU group, with significantly better breast symmetry and global aesthetic evaluation (P = .021).
conclusionsPU-coated implants offer a safer and more effective approach in immediate prepectoral breast reconstruction, with reduced complication rates and improved aesthetic outcomes compared with ADM-covered implants. Patient-specific anatomical and oncologic factors should guide implant selection to optimize surgical outcomes. LEVEL OF EVIDENCE: 4 (THERAPEUTIC):
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