ArticleThe western journal of emergency medicine2025
Biological Variation of Corrected QT and QRS Electrocardiogram Intervals: Interpreting Results of Drug-induced Prolongation.
Article in The western journal of emergency medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Use of Corrected QT Cutoffs Derived from Biological Variation to Predict Adverse Events Due to Antipsychotic Drugs: Case Report.Clinical practice and cases in emergency medicine · 2026Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionToxicologists use a universal threshold to determine QRS and QTc prolongation in poisoned patients. Further understanding of the biologic variance of these intervals may allow for a more personalized approach to assessing the clinical significance of electrocardiogram (ECG) changes in these patients.
methodsWe recruited six male and six female healthy subjects. Standard 12-lead ECGs were performed in duplicate once per week for four consecutive weeks. We calculated the mean and standard deviation, the coefficient of variance (CV) for replicate readings (CV
resultsThe median QRS interval for healthy males (103.4 milliseconds [ms]) was statistically higher than that for females (88.6 ms) in our study (P < .05). The CV
conclusionWe demonstrated a significant difference in QRS duration between healthy males and females as well as a low II, particularly for the QRS interval, indicating that the CV
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