Evidence map›Paper›PMID 40794662›Full record

SynthesisClinical infectious diseases : an official publication of the Infectious Diseases Society of America2025

A Systematic Review of Health-Related Quality-of-Life Measurement in Patients With Complicated Intraabdominal Infections.

Abigail Rader, Felicia Ruffin, Caitlin Fai, Karen D Barton, Lesley A Skalla, Tsai-Wei Wang, Megan Oakes, Katherine N Sutton, Julie Miller, Deborah Collyar and 4 more

Abstract readSystematic Review
In one paragraph

Synthesis in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Patient-Reported Outcomes and Health-Related Quality-of-Life Measures in Infectious Diseases Studies and Clinical Practice.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Abigail RaderDepartment of Population Health Sciences, Duke University School of Medicine, Durham, North Carolina, USA.ORCID 0000-0002-6315-9129
Felicia RuffinDivision of Infectious Diseases, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA.ORCID 0000-0003-2176-6462
Caitlin FaiTufts University School of Medicine and Division of Geographic Medicine and Infectious Diseases, Tufts Medical Center, Boston, Massachusetts, USA.
Karen D BartonDuke University Medical Center Library & Archives, Duke University School of Medicine, Durham, North Carolina, USA.ORCID 0000-0002-2014-8139
Lesley A SkallaDuke University Medical Center Library & Archives, Duke University School of Medicine, Durham, North Carolina, USA.ORCID 0000-0001-5121-6010
Tsai-Wei WangDepartment of Population Health Sciences, Duke University School of Medicine, Durham, North Carolina, USA.ORCID 0000-0002-0156-8867
Megan OakesDepartment of Population Health Sciences, Duke University School of Medicine, Durham, North Carolina, USA.
Katherine N SuttonDepartment of Population Health Sciences, Duke University School of Medicine, Durham, North Carolina, USA.ORCID 0000-0002-3064-5294
Julie MillerDepartment of Population Health Sciences, Duke University School of Medicine, Durham, North Carolina, USA.ORCID 0009-0005-9704-0520
Deborah CollyarPatient Advocates In Research, Danville, California, USA.ORCID 0000-0003-0886-0964
Helen W BoucherTufts University School of Medicine and Division of Geographic Medicine and Infectious Diseases, Tufts Medical Center, Boston, Massachusetts, USA.
Sarah B DoernbergDivision of Infectious Diseases, Department of Medicine, University of California-San Francisco, San Francisco, California, USA.ORCID 0000-0003-1727-6014
Bryce B ReeveDepartment of Population Health Sciences, Duke University School of Medicine, Durham, North Carolina, USA.ORCID 0000-0002-6709-8714
Heather A KingDepartment of Population Health Sciences, Duke University School of Medicine, Durham, North Carolina, USA.

Funding

Durham VA Health Care SystemHSRD VA CIN 13-410National Institute of Allergy and Infectious Diseases UM1AI104681)
6 · The paper itself

Abstract

backgroundIn this systematic review, we assessed health-related quality-of-life (HRQoL) measures in patients with complicated intraabdominal infections (cIAIs) commonly associated with sepsis and evaluated the impact of cIAIs on HRQoL.

methodsFollowing a prospectively registered protocol in PROSPERO (CRD42021255827), we searched electronic databases, including MEDLINE (PubMed), EMBASE (Elsevier), and CINAHL (EBSCO), from database inception through September 2022 to identify studies that measured HRQoL in patients with cIAIs.

resultsWe identified 93 articles that included 45 HRQoL measures: 32 generic, 5 condition-specific, and 8 symptom-specific. Additionally, in 12 studies, researchers developed their own HRQoL questions or questionnaires. The measures evaluated symptom status (30 measures), functioning (39 measures), general health perceptions (8 measures), and overall HRQoL (12 measures). Article results showed that HRQoL in patients with cIAIs improved over time post-treatment and that symptoms, including pain, fatigue, and incontinence, were common. Only the diverticulitis quality-of-life (DV-QoL) instrument had been psychometrically tested in patients with cIAI.

conclusionsThis review highlights the need for disease-specific HRQoL measures that are rigorously tested and validated in patient populations with cIAIs, which can be informed by the DV-QoL.

Indexed as

Intraabdominal InfectionsQuality of LifeHumansSepsisSurveys and Questionnairescomplicated intraabdominal infectionHRQOLpatient-reported outcomequality of lifesystematic review

Identifiers

PMID40794662
PMCPMC12341885

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.