Evidence map›Paper›PMID 40794661›Full record

SynthesisClinical infectious diseases : an official publication of the Infectious Diseases Society of America2025

A Systematic Review of Health-Related Quality-of-Life Measurement in Patients With Acute Bacterial Skin and Skin Structure Infections.

Katherine N Sutton, Emily Lydon, Abigail Rader, Karen D Barton, Lesley A Skalla, Tsai-Wei Wang, Felicia Ruffin, Megan Oakes, Julie Miller, Deborah Collyar and 3 more

Abstract readSystematic Review
In one paragraph

Synthesis in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Methicillin-resistant Staphylococcus aureus.Nature reviews. Disease primers · 2026
    Review
  3. Article
  4. Patient-Reported Outcomes and Health-Related Quality-of-Life Measures in Infectious Diseases Studies and Clinical Practice.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Katherine N SuttonDepartment of Population Health Sciences, Duke University School of Medicine, Durham, North Carolina, USA.ORCID 0000-0002-3064-5294
Emily LydonDivision of Infectious Diseases, Department of Medicine, University of California San Francisco, San Francisco, California, USA.
Abigail RaderDepartment of Population Health Sciences, Duke University School of Medicine, Durham, North Carolina, USA.
Karen D BartonDuke University Medical Center Library, Durham, North Carolina, USA.ORCID 0000-0002-2014-8139
Lesley A SkallaDuke University Medical Center Library, Durham, North Carolina, USA.
Tsai-Wei WangDepartment of Population Health Sciences, Duke University School of Medicine, Durham, North Carolina, USA.ORCID 0000-0002-0156-8867
Felicia RuffinDivision of Infectious Diseases, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA.ORCID 0000-0003-2176-6462
Megan OakesDepartment of Population Health Sciences, Duke University School of Medicine, Durham, North Carolina, USA.
Julie MillerDepartment of Population Health Sciences, Duke University School of Medicine, Durham, North Carolina, USA.ORCID 0009-0005-9704-0520
Deborah CollyarPatient Advocates In Research (PAIR), Danville, California, USA.ORCID 0000-0003-0886-0964
Helen W BoucherTufts University School of Medicine and Division of Geographic Medicine and Infectious Diseases, Tufts Medical Center, Boston, Massachusetts, USA.
Sarah B DoernbergDivision of Infectious Diseases, Department of Medicine, University of California San Francisco, San Francisco, California, USA.ORCID 0000-0003-1727-6014
Heather A KingDepartment of Population Health Sciences, Duke University School of Medicine, Durham, North Carolina, USA.

Funding

Antibacterial Resistance Leadership Group (ARLG)UM1AI104681 · NIAID · DUKE UNIVERSITY · PI Vance G. Fowler, Henry F HENRY CHAMBERS · 2013 to 2026
$180.8M
National Institute of Allergy and Infectious DiseasesNIH HHS UM1AI104681
6 · The paper itself

Abstract

backgroundAcute bacterial skin and skin structure infections (ABSSSIs) can diminish patients' health-related quality of life (HRQoL). We performed a systematic review to determine how HRQoL has been measured in patients with ABSSSIs.

methodsWe searched MEDLINE (PubMed), Embase (Elsevier), and CINAHL (EBSCO) for articles published between database inception and 14 October 2022, following a prospectively registered protocol in PROSPERO (CRD42021225414).

resultsWe identified 37 articles that employed 42 distinct measures: 26 generic measures assessing HRQoL; 14 condition-specific measures, including repurposed dermatologic or surgical HRQoL measures; and 2 author-developed questionnaires assessing treatment-related HRQoL. We found reduced HRQoL for patients experiencing ABSSSIs, which usually exhibited rapid onset and resolution. Pain had the greatest negative impact on HRQoL, and the most common HRQoL domain impacted was physical functioning.

conclusionsProgress has been made in the development and use of HRQoL measures, yet we did not identify a repurposed or novel tool that best captures HRQoL in patients with ABSSSI.

Indexed as

Quality of LifeSkin Diseases, BacterialAcute DiseaseHumansSurveys and Questionnairesacute bacterial skin and skin structure infectionsbacterial skin infectionshealth-related quality of lifepatient-reported outcomessystematic review

Identifiers

PMID40794661
PMCPMC12341922

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.