SynthesisClinical infectious diseases : an official publication of the Infectious Diseases Society of America2025
A Systematic Review of Health-Related Quality-of-Life Measurement in Patients With Hospital-Acquired/Ventilator-Associated Bacterial Pneumonia.
Synthesis in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Comparing Patient and Clinician Perceptions of Health-Related Quality of Life in Urinary Tract Infections.JAMA network open · 2026Article
- Patient-Reported Outcomes and Health-Related Quality-of-Life Measures in Infectious Diseases Studies and Clinical Practice.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025Article
Corrections and comments
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Authors and funding
14 authors.
Funding
Abstract
backgroundWe conducted a systematic review to gain insight into how health-related quality of life (HRQoL) is measured and reported in hospital-acquired bacterial pneumonia (HABP) and ventilator-associated bacterial pneumonia (VABP), common causes of disease and death in hospitalized patients.
methodsFollowing a prospectively registered protocol in PROSPERO (CRD42021253579), we searched electronic databases, including MEDLINE (PubMed), EMBASE (Elsevier), and CINAHL (EBSCO) from database inception through October 2022 to identify studies measuring HRQoL in patients with HABP and/or VABP.
resultsOf 2633 studies identified, 5 articles met our inclusion criteria. Of the 5 included studies, 3 were performed in patients with traumatic brain injury; 4 studies were conducted at a single hospital site, and 1 was from a multicenter registry. Measures to assess HRQoL varied between studies and primarily included the Glasgow Outcome Scale-Extended and the 36-item Short Form. All studies were of mid- to high quality and concluded that HABP/VABP decreased multiple domains of HRQoL, although it was difficult to determine whether this was below the background decrease in HRQoL for comorbid medical conditions.
conclusionsOverall, there is limited measurement of HRQoL in patients with HABP/VABP; however, existing data indicate that HABP/VABP impairs multiple domains of HRQoL. More research is needed to standardize measurements of HRQoL and its application in patients with HABP/VABP.
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