ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2025
Developing, Analyzing, and Interpreting Outcome Assessments to Improve Endpoints in Infectious Diseases Clinical Research.
Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Patient-Reported Outcomes and Health-Related Quality-of-Life Measures in Infectious Diseases Studies and Clinical Practice.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Evidence from clinical research studies, in addition to patient values and clinical experience, helps practitioners best apply medical interventions to clinical practice. Part of evaluating the evidence is understanding the outcomes used as endpoints in research studies. The most direct evidence of patient benefit comes from endpoints that evaluate the effects of interventions on patient survival, symptoms, and function, and the impact of symptoms and function on health-related quality of life. In this article, we discuss how to develop endpoints for clinical research studies focusing on patient-reported outcome measures, including those measuring patient symptoms, function, and health-related quality of life. We discuss the process for determining (1) which concepts to measure, including which concepts are most relevant to patients (content validity); (2) who performs the measurement and which measurement properties to use (construct validity); and (3) how to analyze and interpret the results obtained using the chosen measurements.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.