SynthesisEuropean journal of preventive cardiology2026
Sex influence on in-hospital and long-term prognosis of myocardial infarction with non-obstructive coronary artery disease: a systematic review and meta-analysis.
Synthesis in European journal of preventive cardiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- What we don't see, we don't treat: sex, risk, and recognition in myocardial infarction with non-obstructive coronary arteries.European journal of preventive cardiology · 2026Article
- Gender- and sex-dependent variations in heart failure and cardiomyopathies: a review of the literature.Naunyn-Schmiedeberg's archives of pharmacology · 2026Review
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Authors and funding
4 authors.
Funding
Abstract
aimsThe incidence of myocardial infarction with non-obstructive coronary artery disease (MINOCA) is higher in women than in men, but sex influence on prognosis is unclear. The aim of this study was to evaluate overall mortality and different major adverse cardiovascular events (MACE) during hospitalization and at follow-up in men and women with MINOCA. METHODS AND
resultsProspective and retrospective studies reporting on the association between sex and adverse clinical outcomes in MINOCA patients were eligible. In-hospital and at follow-up outcomes in the overall pooled populations and odds ratios (ORs) with 95% confidence intervals (CIs) were calculated. Fifteen studies, encompassing 42 870 patients [62.0 (3.7) years, 25 172 females (58.7%)], were included. A total of 277 patients died during hospitalization, and 2236 deaths occurred during a mean follow-up of 3.5 (0.9) years. Pooled analyses demonstrated no sex differences in in-hospital mortality (OR: 1.05; 95% CI: 0.82-1.34; I2 = 0%) or all-cause death at follow-up (OR: 0.93; 95% CI: 0.76-1.13; I2 = 54%). In the long term, men had a lower risk of non-fatal stroke (OR: 0.77; 95% CI: 0.60-0.99; I2 = 0%), but no significant sex differences were detected for other MACE. In women, MINOCA had a lower risk of in-hospital mortality than MI due to coronary artery disease (MI-CAD; OR: 0.39; 95% CI: 0.21-0.72; I2 = 70%), while no relevant differences were found in males.
conclusionSex does not seem to influence MINOCA prognosis, except for a higher incidence of stroke during follow-up found in women. In females, MINOCA has lower in-hospital mortality than MI-CAD.
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Registered trials
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