Evidence map›Paper›PMID 40794587›Full record

ArticleClinical journal of oncology nursing2025

Blinatumomab Administration in Pediatric B-Lineage ALL: Expert Recommendations From the Children's Oncology Group.

Holly R Kubaney, Kathleen E Montgomery, Lauren Guidry, Maki Okada, Katelyn Oranges, Shelby Smith, Megan Elizabeth Wegter, Olga Militano, Sumit Gupta, Rachel Rau and 1 more

Abstract read
In one paragraph

Article in Clinical journal of oncology nursing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Holly R KubaneyHolly R. Kubaney.
Kathleen E MontgomeryKathleen E. Montgomery.
Lauren GuidryLauren Guidry.
Maki OkadaMaki Okada.
Katelyn OrangesKatelyn Oranges.
Shelby SmithShelby Smith.
Megan Elizabeth WegterMegan Elizabeth Wegter.
Olga MilitanoOlga Militano.
Sumit GuptaSumit Gupta.
Rachel RauRachel E. Rau.
Sue ZupanecSue Zupanec.

Funding

NCTN BIQSFP ANBL1531 (NRT)U10CA180886 · NCI · PUBLIC HEALTH INSTITUTE · PI Douglas S. Hawkins · 2014 to 2026
$390.6M
NCI NIH HHS U10 CA180886
6 · The paper itself

Abstract

backgroundThe addition of blinatumomab to chemotherapy is the new standard of care for most pediatric patients with B-lineage acute lymphoblastic leukemia (B-ALL), and its use has increased rapidly. Administering blinatumomab to pediatric patients is associated with a spectrum of unique challenges, resulting in variable practices across institutions.

objectivesThis article presents expert recommendations for blinatumomab administration in patients with pediatric B-ALL.

methodsPediatric oncology nurses, physicians, and pharmacists collated current evidence and Children's Oncology Group institutional experiences to identify considerations for planning for blinatumomab administration, initiating and managing infusions, and monitoring for adverse events.

findingsEngaging patients, families, and clinicians promotes care transitions between inpatient and outpatient settings and minimizes complications. Ongoing institutional commitment to monitor and capture emerging trends in blinatumomab administration can inform future optimal care practices.

Indexed as

Antibodies, BispecificAntineoplastic AgentsPractice Guidelines as TopicPrecursor B-Cell Lymphoblastic Leukemia-LymphomaAdolescentChildChild, PreschoolFemaleHumansInfantMaleAntibodies, BispecificAntineoplastic AgentsblinatumomabblinatumomabB-lineage acute lymphoblastic leukemiahome infusion therapy

Identifiers

PMID40794587
PMCPMC12339268

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.