Evidence map›Paper›PMID 40794561›Full record

ArticleBJS open2025

Evaluation of sarcopenia and myosteatosis to determine the impact on mortality after emergency laparotomy.

Richard P T Evans, Dimit Raveshia, Mei Sien Liew, Anna Jackowski, Aaron Kisiel, Ewen A Griffiths, Benjamin H L Tan

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Article in BJS open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Richard P T EvansDepartment of Upper Gastrointestinal Surgery, Queen Elizabeth Hospital, Birmingham, UK.
Dimit RaveshiaDepartment of Upper Gastrointestinal Surgery, Queen Elizabeth Hospital, Birmingham, UK.ORCID 0000-0002-9394-6289
Mei Sien LiewDepartment of Upper Gastrointestinal Surgery, Queen Elizabeth Hospital, Birmingham, UK.
Anna JackowskiDepartment of Upper Gastrointestinal Surgery, Queen Elizabeth Hospital, Birmingham, UK.
Aaron KisielDepartment of Upper Gastrointestinal Surgery, Queen Elizabeth Hospital, Birmingham, UK.
Ewen A GriffithsDepartment of Upper Gastrointestinal Surgery, Queen Elizabeth Hospital, Birmingham, UK.ORCID 0000-0001-6630-3547
Benjamin H L TanDepartment of Upper Gastrointestinal Surgery, Queen Elizabeth Hospital, Birmingham, UK.

Funding

University of Birmingham
6 · The paper itself

Abstract

backgroundEmergency laparotomy is performed for a wide range of life-threatening conditions and is associated with significant morbidity and mortality. Risk prediction models facilitate accurate communication of operative risk with patients and relatives, in addition to benchmarking unit outcomes. Greater understanding of the impact of sarcopenia or myosteatosis will encourage the adoption of routine radiological reporting of body composition and the incorporation of skeletal muscle gauge (SMG) into risk prediction models. This study investigated the prognostic significance of SMG, an aggregate assessment of sarcopenia or myosteatosis, in patients who had undergone an emergency non-trauma-related laparotomy.

methodsThis was a retrospective cohort study of patients aged ≥ 18 years who underwent an emergency laparotomy at the Queen Elizabeth Hospital between January 2014 and December 2020. Body composition and patient outcomes were analysed.

resultsIn all, 1090 patients with a mean(standard deviation) age of 62.3(17.5) years underwent emergency laparotomy (bowel obstruction, 52.7%; perforation, 26.3%; ischaemia, 9.5%). Overall 30- and 90-day mortality was 10.0% and 11.6%, respectively. On multivariate analysis, low SMG was associated with worse 30- and 90-day mortality, with odds ratios of 2.12 (95% confidence interval (c.i.) 1.18 to 3.83; P = 0.012) and 2.64 (95% c.i. 1.55 to 4.48; P < 0.001), respectively. Low SMG was also associated with an increased length of hospital stay (odds ratio 1.45; 95% c.i. 1.22 to 1.72; P < 0.001).

conclusionA low SMG was associated with increased postoperative mortality and length of hospital stay after emergency laparotomy. Patients undergoing computed tomography imaging for acute abdominal pain should undergo routine reporting of body composition.

Indexed as

LaparotomyMuscle, SkeletalSarcopeniaAgedAged, 80 and overBody CompositionEmergenciesFemaleHumansIntestinal ObstructionLength of StayMaleMiddle AgedPrognosisRetrospective StudiesRisk Assessmentemergency laparotomymorbiditymortalitymyosteatosissarcopenia

Identifiers

PMID40794561
PMCPMC12341672

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.