ReviewThe Journal of infectious diseases2026
The Emerging Role of Immunothrombosis in the Control and Pathogenesis of Mycobacterium tuberculosis.
Review in The Journal of infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Nomogram for predicting prognostic risk in severe pulmonary tuberculosis: a retrospective analysis from the MIMIC-IV database.Journal of thoracic disease · 2026Article
- A plasma proteomic signature of the actin-coagulation axis accurately predicts progression to active tuberculosis.Frontiers in microbiology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Greater understanding of the immunopathogenesis of tuberculosis is critical for developing novel therapies. Here, we propose that immunothrombosis plays an important role in the immune response to Mycobacterium tuberculosis. This interplay among macrophages, neutrophils, and platelets leads to microthrombosis at the site of infection, trapping the mycobacterium to prevent dissemination. We explore how dysregulated immunothrombosis might contribute to tuberculosis pathogenesis, with excessive microthrombosis driving drug resistance, leading to lung damage and venous thromboembolism. Further research into these poorly understood mechanisms could identify options for host-directed therapies to ameliorate immunothrombosis, with its attendant tissue destruction, and reduce the burden of resistance.
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Registered trials
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