Evidence map›Paper›PMID 40794377›Full record

ReviewCurrent neurology and neuroscience reports2025

Central Nervous System Tumors in Adolescents and Young Adults.

Jaime Godoy-Santin, Abitha Suthakaran, Julie Bennett, Mary Jane Lim-Fat

Abstract readReview
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In one paragraph

Review in Current neurology and neuroscience reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jaime Godoy-SantinDivision of Neurology, Department of Medicine, Sunnybrook Health Sciences Centre, Faculty of Medicine, University of Toronto, Toronto, ON, Canada. jaime.godoysantin@sunnybrook.ca.
Abitha SuthakaranDivision of Hematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada.
Julie BennettDivision of Hematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada.
Mary Jane Lim-FatDivision of Neurology, Department of Medicine, Sunnybrook Health Sciences Centre, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpuse of reviewBrain tumors in adolescents and young adults (AYAs), defined as individuals aged 15 to 39 years, represent a heterogeneous group with a broad prognostic spectrum and unique clinical challenges. As many AYAs experience prolonged survival, treatment decisions must balance efficacy with the risk of long-term side effects. This review outlines the initial diagnostic approach and highlights recent therapeutic advances. RECENT

findingsAdvances in molecular diagnostics have refined tumor classification, enabled risk stratification, and supported the development of novel therapies. In selected tumors, targeted therapies are increasingly replacing conventional chemotherapy and radiation. Despite progress, treatment options for high-grade gliomas remain limited. A deeper understanding of oncogenic pathways has led to promising targeted therapies. However, more studies are needed to define optimal treatment combinations, sequencing, and strategies to overcome resistance. Multidisciplinary care is essential to address both oncologic outcomes and survivorship.

Indexed as

Brain NeoplasmsCentral Nervous System NeoplasmsAdolescentAdultHumansYoung AdultAdolescents and young adultsBrain tumorsEpendymomaGlioblastomaGliomasMedulloblastoma

Identifiers

PMID40794377

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.