Evidence map›Paper›PMID 40794295›Full record

SynthesisHernia : the journal of hernias and abdominal wall surgery2025

Impact of different neurectomy techniques on managing chronic pain after inguinal hernia repair: a meta-analysis and systematic review.

Emmanouil Charitakis, Eyman Haj-Ali, Farah Al Hasani-Pfister, Baraa Saad, Niklas Ortlieb, Amanda Haberstroh, Florian Ponholzer, Stephanie Taha-Mehlitz, Lisa-Marie Schupp, Robert Christian Bauer and 4 more

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Hernia : the journal of hernias and abdominal wall surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Emmanouil CharitakisFaculty of Medicine, University of Basel, Basel, Switzerland.
Eyman Haj-AliEmergency Department, Al-Habib Medical Group, Riyadh, Saudi Arabia.
Farah Al Hasani-PfisterDepartment of Visceral Surgery, Cantonal Hospital, Baselland, Switzerland.
Baraa SaadFaculty of Medicine, Royal Lancaster Infirmary, Lancaster, UK.
Niklas OrtliebMedoc Swiss, Data Science and Statistics, Basel, Switzerland.
Amanda HaberstrohLaupus Health Sciences Library, East Carolina University, Greenville, NC, USA.
Florian PonholzerDepartment of Visceral, Transplant, and Thoracic Surgery, Center of Operative Medicine, Medical University of Innsbruck, Innsbruck, Austria.
Stephanie Taha-MehlitzClarunis, University Centre for Gastrointestinal and Liver Diseases, St. Clara Hospital and University Hospital, Basel, 4002, Switzerland.
Lisa-Marie SchuppDepartment of Visceral Surgery, Cantonal Hospital, Baselland, Switzerland.
Robert Christian BauerDepartment of Visceral Surgery, Cantonal Hospital, Baselland, Switzerland.
Sebastian LammDepartment of Visceral Surgery, Cantonal Hospital, Baselland, Switzerland.
Daniel M FreyDepartment of Visceral Surgery, Cantonal Hospital Baden, Baden, Switzerland.
Robert RosenbergDepartment of Visceral Surgery, Cantonal Hospital, Baselland, Switzerland.
Anas TahaDepartment of Visceral Surgery, Cantonal Hospital, Baselland, Switzerland. anas.taha@unibas.ch.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis meta-analysis aims to analyze the outcomes of neurectomy for treating chronic post herniorrhaphy pain (CPIP), with a focus on the efficacy of various surgical approaches (open, laparoscopic transabdominal, endoscopic retroperitoneal and combined approach), and types of neurectomy-single, double and triple.

methodsThe research was registered with PROSPERO (CRD42023475401). A search in MEDLINE, Embase, Scopus, and Cochrane Central databases was conducted from the inception to November 2023. All participants aged 18 years and older who underwent neurectomy for treating CPIP were included. PRISMA guidelines were followed, selecting only randomized controlled trials, cohort studies and case series. A random-effects model was used for single-arm analyses, while the inverse variance and Mantel-Haenszel methods were employed for two-arm analyses.

resultsThe analysis includes fifteen studies involving 701 patients. Following neurectomy, 90% of the patients experienced an improvement in pain overall. Only 9.4% of the patients had postoperative complications. Among the surgical types, triple neurectomy demonstrated the highest overall pain improvement rate at 98.2%. Double neurectomy showed the highest rate of complete pain relief at 80.1%, but it also had a higher complication rate of 15.3%. In terms of surgical approach, the endoscopic retroperitoneal method not only had the highest overall improvement rate of 95.5% compared to other approaches but also the highest complication rate of 28.7%.

conclusionNeurectomy was shown to be an effective treatment for neuropathic CPIP across various surgical techniques. Randomized controlled trials would be of vital importance to facilitate the evolution of surgical strategy and patient outcomes.

Indexed as

Chronic PainHernia, InguinalHerniorrhaphyPostoperative PainHumansChronic painInguinal herniaMeta-analysisNeurectomyPain managementPostherniorrhaphy

Identifiers

PMID40794295
PMCPMC12343651

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.