ReviewThe ultrasound journal2025
Advances and innovations in ultrasound-based tumor management: current applications and emerging directions.
Review in The ultrasound journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Multiparametric Abdominal Ultrasound as a Source of Imaging Biomarkers in Predictive and Personalized Medicine: A Narrative Review.Diagnostics (Basel, Switzerland) · 2026Review
- Biopsy Needle Integrated with Rotational Oblique Spectral Ultrasound (ROSUS) Imaging.Sensors (Basel, Switzerland) · 2026Article
- Case Report: Alternative biopsy targets plus CEUS-guided omental puncture: enabling CLDN18.2 detection and precision therapy enrollment in pancreatic cancer.Frontiers in radiology · 2026Article
- Ultrasonography of Widespread Metastases in Advanced Gastric Signet Ring Cell Carcinoma.Diagnostics (Basel, Switzerland) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
As a crucial medical imaging modality, ultrasonography has emerged as a pivotal tool for tumor diagnosis and treatment owing to its non-invasive nature, real-time imaging capability, and superior resolution. Recent technological advancements have demonstrated unique advantages in early tumor screening, staging, and localization. Contrast-enhanced ultrasound (CEUS), utilizing microbubbles (MBs) and nanobubbles (NBs) to target vascular biomarkers, significantly enhances tumor visualization and demonstrates high sensitivity in molecular imaging. Multimodal ultrasound (MU), incorporating techniques such as elastography and automated breast volume scanning (ABVS), achieves improved diagnostic accuracy when combined with MRI/CT. The applications of ultrasound in localized and systemic tumor therapy have expanded considerably. High-intensity focused ultrasound (HIFU) enables thermal ablation of solid tumors, while low-intensity focused ultrasound (LIFU) facilitates sonodynamic therapy (SDT) through reactive oxygen species (ROS) generation mediated by sonosensitizers. Ultrasound-assisted drug delivery systems (US-DDS) leverage MB/NB cavitation effects to enhance chemotherapeutic agent delivery efficiency, overcome biological barriers, including the blood-brain barrier, and modulate immune responses. These technological breakthroughs have provided novel therapeutic options for cancer patients, garnering significant clinical interest. This review systematically examines current applications of ultrasound imaging and therapy in oncology, evaluates its potential clinical value, analyzes existing technical limitations, and discusses future development prospects. The article aims to provide innovative perspectives for tumor diagnosis and treatment while offering references for clinical practice.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.