Evidence map›Paper›PMID 40794234›Full record

ArticleDigestive diseases and sciences2026

Low Yield of Surveillance Endoscopy in Severe Oesophagitis: A 1700-Patient Retrospective Cohort Study.

T Matthews, C Barry, S M Connor, H Tyrrell, R Wilson, A Billur, G Bennett, B Kelleher, C Lahiff, J Leyden and 3 more

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Article in Digestive diseases and sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

13 authors.

T MatthewsDepartment of Gastroenterology, The Mater Hospital, Dublin, Ireland. thomasmatthews@mater.ie.
C BarryDepartment of Gastroenterology, The Mater Hospital, Dublin, Ireland.
S M ConnorDepartment of Gastroenterology, The Mater Hospital, Dublin, Ireland.
H TyrrellDepartment of Gastroenterology, The Mater Hospital, Dublin, Ireland.
R WilsonDepartment of Gastroenterology, The Mater Hospital, Dublin, Ireland.
A BillurSchool of Medicine, University College Dublin, Belfield, Dublin 4, Ireland.
G BennettDepartment of Gastroenterology, The Mater Hospital, Dublin, Ireland.
B KelleherDepartment of Gastroenterology, The Mater Hospital, Dublin, Ireland.
C LahiffDepartment of Gastroenterology, The Mater Hospital, Dublin, Ireland.
J LeydenDepartment of Gastroenterology, The Mater Hospital, Dublin, Ireland.
N RamlaulDepartment of Gastroenterology, The Mater Hospital, Dublin, Ireland.
S StewartDepartment of Gastroenterology, The Mater Hospital, Dublin, Ireland.
O CraigDepartment of Gastroenterology, The Mater Hospital, Dublin, Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGuidelines recommend re-evaluation of severe oesophagitis to detect occult malignancy and Barrett's oesophagus (BE), but the utility and resource implications of this practice are unclear.

aimsTo assess the diagnostic yield, predictors, and resource implications of surveillance endoscopy in patients with severe (LA Grade C/D) oesophagitis.

methodsWe conducted a retrospective cohort study of 1700 index cases of severe oesophagitis over 18.5 years. Surveillance outcomes were assessed using endoscopy and histology databases. Univariate and multivariate logit regressions were used to explore associations with malignancy, BE and surveillance.

resultsOnly 6 oesophageal cancers (0.35%) were diagnosed, 3 at index. Of 717 re-evaluated patients (42.2%), just one malignancy was detected on surveillance. BE was newly identified in 48 patients (6.7% of re-evaluations), with no occult dysplasia found. No malignancies were diagnosed in the 980 patients not re-evaluated. The total cost of surveillance was €580,215.

conclusionsRoutine endoscopic surveillance for LA Grade C/D oesophagitis had a low diagnostic yield and high cost. These findings suggest that current guideline recommendations may need revision in favour of risk-stratified follow-up to optimise healthcare resource use.

Indexed as

Barrett EsophagusEsophageal NeoplasmsEsophagitisEsophagoscopyAdultAgedFemaleHumansMaleMiddle AgedPopulation SurveillanceRetrospective StudiesSeverity of Illness IndexBarrett’s oesophagusEndoscopyOesophageal cancerOesophagitis

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.