SynthesisHernia : the journal of hernias and abdominal wall surgery2025
Incisional and parastomal hernias after harvesting of Vertical Rectus Abdominis Myocutaneous (VRAM) flaps: incidence, treatment options and outcomes.
Synthesis in Hernia : the journal of hernias and abdominal wall surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimThe Vertical Rectus Abdominis Myocutaneous (VRAM) flap is a versatile reconstructive technique but is associated with donor-site morbidity, including incisional hernia (IH) and parastomal hernia (PSH). Our aim was to assess the incidence, treatment options and outcomes of IH and PSH following VRAM flap harvest.
methodA systematic search was conducted in PubMed, Embase and Scopus (to June 2024) using predefined terms. Studies with at least 10 participants and a follow-up of minimum one year were included. Two reviewers independently performed study selection, data extraction, quality of evidence (GRADE) and risk of bias (ROBINS-I, RoB-2). Primary outcomes were IH and PSH incidence.
results24 studies (2200 patients) were included (19 retrospective cohorts, 3 case series, 2 randomized controlled trials). IH was reported in 10.2% (226/2200) and PSH in 19.2% (219/1143) of patients over a mean follow-up of 31 months (range: 12-66). Studies focused on prophylactic techniques included robotic harvesting (n = 1), fascia-sparing harvesting (n = 5), component separation (n = 6) and mesh-assisted closure (n = 16). Hernia repair involved mesh (n = 3) and primary suture (n = 1).
conclusionDespite advances in prophylactic techniques for hernia prevention, significant challenges remain, including high heterogeneity in clinical diagnosis, follow-up duration, and surgical techniques. While some methods, such as fascia-sparing approaches, component separation, and mesh reinforcement show promising outcomes in reducing IH and PSH incidence, a lack of comparative studies prevents reaching a clear consensus. Future research should focus on larger scale studies and expert opinions to develop clinical recommendations for hernia prophylaxis and repair.
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Identifiers
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Registered trials
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