Evidence map›Paper›PMID 40794102›Full record

ArticleeLife2025

An Hfq-dependent post-transcriptional mechanism fine tunes RecB expression in

Irina Kalita, Ira Alexandra Iosub, Lorna McLaren, Louise Goossens, Sander Granneman, Meriem El Karoui

Abstract read
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Irina KalitaCentre for Engineering Biology, University of Edinburgh, Edinburgh, United Kingdom.ORCID https://orcid.org/0000-0002-0127-077X
Ira Alexandra IosubCentre for Engineering Biology, University of Edinburgh, Edinburgh, United Kingdom.
Lorna McLarenCentre for Engineering Biology, University of Edinburgh, Edinburgh, United Kingdom.
Louise GoossensCentre for Engineering Biology, University of Edinburgh, Edinburgh, United Kingdom.
Sander GrannemanCentre for Engineering Biology, University of Edinburgh, Edinburgh, United Kingdom.
Meriem El KarouiCentre for Engineering Biology, University of Edinburgh, Edinburgh, United Kingdom.ORCID https://orcid.org/0000-0003-2522-613X

Funding

Biotechnology and Biological Sciences Research Council BB/S008012/1Medical Research Council MR/R008205/1Wellcome TrustWellcome Trust 10.35802/092076Wellcome Trust 10.35802/102334Wellcome Trust 10.35802/205008
6 · The paper itself

Abstract

All living organisms have developed strategies to respond to chromosomal damage and preserve genome integrity. One such response is the repair of DNA double-strand breaks (DSBs), one of the most toxic forms of DNA lesions. In

Indexed as

Escherichia coliEscherichia coli ProteinsExodeoxyribonuclease VGene Expression Regulation, BacterialHost Factor 1 ProteinProtein BindingRNA, MessengerEscherichia coli ProteinsExodeoxyribonuclease VHfq protein, E coliHost Factor 1 ProteinRNA, MessengerchromosomesDNA repairE. coligene expressionHfq proteinnoise suppressionphysics of living systemspost-transcriptional regulationRecBCD enzyme

Identifiers

PMID40794102
PMCPMC12342828

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.