Evidence map›Paper›PMID 40794100›Full record

ArticleMicrobial genomics2025

Plasmid prevalence is independent of antibiotic resistance in environmental

Danya Gewurz, Suhyeon Kim, Lorenza Bartu, Abhishek Sharma, Joanna Ciol Harrison, Ivan Lee, Nicole C Rondeau, Jj L Miranda, Brian J Mailloux, Kerry A Hamilton and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbial genomics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Danya GewurzDepartment of Biology, Barnard College of Columbia University, New York, NY, USA.
Suhyeon KimDepartment of Chemical Engineering, University of Rochester, Rochester, NY, USA.
Lorenza BartuDepartment of immunology and Immunotherapy, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Abhishek SharmaDepartment of Chemical Engineering, University of Rochester, Rochester, NY, USA.
Joanna Ciol HarrisonSchool of Sustainable Engineering and the Built Environment, 660 S College Ave, Tempe, AZ, USA.
Ivan LeeDepartment of Chemical Engineering, University of Rochester, Rochester, NY, USA.
Nicole C RondeauDepartment of Biology, Barnard College of Columbia University, New York, NY, USA.
Jj L MirandaDepartment of Biology, Barnard College of Columbia University, New York, NY, USA.
Brian J MaillouxDepartment of Environmental Sciences, Barnard College of Columbia University, New York, NY, USA.
Kerry A HamiltonSchool of Sustainable Engineering and the Built Environment, 660 S College Ave, Tempe, AZ, USA.
Allison J LopatkinDepartment of Chemical Engineering, University of Rochester, Rochester, NY, USA.

Funding

Determinants underlying horizontal gene transfer-mediated pathogen successR35GM150871 · NIGMS · UNIVERSITY OF ROCHESTER · PI Allison Lopatkin · 2023 to 2026
$1.7M
NIGMS NIH HHS R35 GM150871
6 · The paper itself

Abstract

The rapid rise of antibiotic-resistant pathogens poses a critical threat to the treatment of infectious diseases. While the spread of antibiotic resistance genes (ARGs) via plasmid conjugation has been extensively studied both in the lab and the clinic, the prevalence and diversity of plasmids in drug-susceptible isolates (e.g. isolates that do not contain ARGs) remain poorly understood. Yet, plasmids in susceptible isolates play a pivotal role as reservoirs, potentially capturing and disseminating ARGs

Indexed as

Drug Resistance, BacterialEnterobacteriaceaePlasmidsAnti-Bacterial AgentsConjugation, GeneticMicrobial Sensitivity TestsWhole Genome SequencingAnti-Bacterial Agentsantibiotic resistancehorizontal gene transferplasmid

Identifiers

PMID40794100
PMCPMC12452199

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.