ArticleAdvanced healthcare materials2025
Biomimetic Mineralization of Keratin Scaffolds for Enamel Regeneration.
Article in Advanced healthcare materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- Extreme Biomimetics: Achievements and Fundamental Challenges for the Future.Biomimetics (Basel, Switzerland) · 2026Review
- Human Enamel Formation: A Scoping Review for Oral Health Professionals.Dentistry journal · 2026Review
- The Journey of Oral Hygiene: The Past, the Present, the Future.Journal of periodontal research · 2026Article
- Biomimetic Design of Dental Restorative Materials: Conceptual Framework and Translational Challenges.Biomimetics (Basel, Switzerland) · 2026Review
- Motif-designed peptide nanofibers as bioactive surface modifiers for biomimetic hydroxyapatite formation on demineralized porous dentin.RSC advances · 2026Article
- Keratin-based protection of enamel against acid-erosion.Frontiers in dental medicine · 2026Article
- Biomimetic Mineralization of Keratin Scaffolds for Enamel Regeneration.Advanced healthcare materials · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
20 authors.
Funding
Abstract
Biomimetic protein-based platforms, with their hierarchical networks and optimal mechanical properties, show promising potential for hard tissue regeneration, including dental enamel. However, achieving aligned enamel-like apatite nanocrystals from organic matrices remains challenging. A simple organic-based approach to re-create the hierarchical enamel structure using water-based keratin films is reported. These films assemble via disulfide bridging into a fibrous organic network and birefringent spherulitic construction of predominant ordered β-sheet conformation. The flexible structure of keratin templates facilitates rearrangement of the secondary structures into α-helices upon mineralization, guiding the ordered growth of apatite nanocrystals. This system has shown potential in repairing early defective dental enamel lesions, restoring both optical appearance and mechanical properties. This study offers a promising, simple, and clinically-friendly method for developing novel protein-based matrices for hard tissue regeneration from naturally abundant sources.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.