ArticleOncoimmunology2025
A laminin α4-CD8
Article in Oncoimmunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
7 authors.
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Abstract
The crossing of the endothelial basement membranes (BMs) is a limiting step for leukocyte diapedesis. Heterotrimeric laminins (LMs) containing α4- and α5-chains are major BM components with opposite effects on transendothelial migration. Here, we examined whether LMα4 levels influence intratumor accumulation of specific immune cells and their impact on prognosis of early-stage colorectal cancer (CRC). Using two independent patient cohorts, we found that LMα4 expression positively correlated with intratumor infiltration of CD8
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