Evidence map›Paper›PMID 40793755›Full record

ArticleJournal of bacteriology2025

The SWIB domain-containing DNA topoisomerase I of

Li Shen, Abigail R Swoboda, Caitlynn Diggs, Shomita Ferdous, Andrew Terrebonne, Amanda Santos, Noel Wolf, Luis Lorenzo Carvajal, Guangming Zhong, Scot P Ouellette and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of bacteriology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Coordinated topoisomerase function shapes the fluoroquinolone response ofbioRxiv : the preprint server for biology · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Li ShenDepartment of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA.ORCID 0000-0001-9869-7317
Abigail R SwobodaDepartment of Pathology, Microbiology, and Immunology, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Caitlynn DiggsDepartment of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA.
Shomita FerdousDepartment of Chemistry and Biochemistry, Florida International University, Miami, Florida, USA.
Andrew TerrebonneDepartment of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA.
Amanda SantosDepartment of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA.
Noel WolfDepartment of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA.
Luis Lorenzo CarvajalDepartment of Chemistry and Biochemistry, Florida International University, Miami, Florida, USA.
Guangming ZhongDepartment of Microbiology, Immunology and Molecular Genetics, University of Texas Health San Antonio, San Antonio, Texas, USA.ORCID 0000-0001-7053-5009
Scot P OuelletteDepartment of Pathology, Microbiology, and Immunology, University of Nebraska Medical Center, Omaha, Nebraska, USA.ORCID 0000-0002-3721-6839
Yuk-Ching Tse-DinhDepartment of Chemistry and Biochemistry, Florida International University, Miami, Florida, USA.ORCID 0000-0002-5616-5176

Funding

Structure, Mechanism and Interactions of Type IA TopoisomerasesR35GM139817 · NIGMS · FLORIDA INTERNATIONAL UNIVERSITY · PI TSE-DINH, YUK-CHING · 2021 to 2025
$1.6M
LSUHSC-New Orleans Postbaccalaureate Research Education Program in Biomedical SciencesR25GM148309 · NIGMS · LSU HEALTH SCIENCES CENTER · PI HARRISON-BERNARD, LISA M. · 2023 to 2024
$453k
CRISPR interference of essential stage-specific gene function in Chlamydia trachomatisR21AI175651 · NIAID · LSU HEALTH SCIENCES CENTER · PI SHEN, LI · 2023 to 2024
$429k
NIAID NIH HHS R21 AI175651NIGMS NIH HHS R25 GM148309NIGMS NIH HHS R35 GM139817NIGMS NIH HHS R35GM139817NIH HHS R21AI175651
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Chlamydia trachomatisDNA, BacterialDNA Topoisomerases, Type IAmino Acid MotifsAmino Acid SequenceAntibodiesBiocatalysisChlamydia InfectionsComputational BiologyEscherichia coliGene DeletionMicrobial ViabilityModels, MolecularMutationProtein FoldingProtein Structure, TertiaryAntibodiesDNA, BacterialDNA Topoisomerases, Type Ichlamydial developmental cycleChlamydia trachomatisCRISPRiDNA relaxationDNA topoisomerase I (TopA)SWIB domaintranscriptional regulation

Identifiers

PMID40793755
PMCPMC12445093

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.