Evidence map›Paper›PMID 40792577›Full record

ArticleActa dermato-venereologica2025

Topical Steroid Withdrawal: Perspectives of Dutch Healthcare Professionals.

Florence Vroman, Charlotte S Schimmel, Lisa P Van der Rijst, Marlies De Graaf, Marjolein De Bruin-Weller, Patrick M J H Kemperman, Dirk Jan Hijnen, Inge M Haeck

Abstract read
In one paragraph

Article in Acta dermato-venereologica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Florence Vroman *Department of Dermatology, University Medical Center Utrecht, University of Utrecht, Utrecht, The Netherlands. F.Vroman@umcutrecht.nl.
Charlotte S Schimmel *Department of Dermatology, University Medical Center Utrecht, University of Utrecht, Utrecht, The Netherlands.
Lisa P Van der RijstDepartment of Dermatology, University Medical Center Utrecht, University of Utrecht, Utrecht, The Netherlands.
Marlies De GraafDepartment of Dermatology, University Medical Center Utrecht, University of Utrecht, Utrecht, The Netherlands.
Marjolein De Bruin-WellerDepartment of Dermatology, University Medical Center Utrecht, University of Utrecht, Utrecht, The Netherlands.
Patrick M J H KempermanDepartment of Dermatology, Amsterdam University Medical Center, Amsterdam Medical center, Amsterdam, The Netherlands.
Dirk Jan HijnenDepartment of Dermatology, Radboud University Medical Center, Radboud University, Nijmegen, The Netherlands.
Inge M HaeckDepartment of Dermatology, University Medical Center Utrecht, University of Utrecht, Utrecht, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Topical steroid withdrawal (TSW) is a highly controversial condition, typically reported following prolonged and/or frequent use of topical corticosteroids. Despite growing public awareness, knowledge of topical steroid withdrawal remains limited. Therefore, this study aimed to explore the perspectives of Dutch healthcare professionals (HCPs) on topical steroid withdrawal. A web-based survey was conducted among 168 Dutch HCPs. The results show that erythema (64.1%) and a burning sensation (60.3%) were the most frequently selected symptoms associated with TSW. The majority of respondents (69.6%) attributed TSW symptoms to atopic dermatitis (AD) flares and/or the adverse effect of topical corticosteroid use. Only a small percentage (12.2%) firmly believed that TSW is a distinct clinical entity, while 17.6% believed that it does not exist. Preferred treatments included using other topical immunomodulators, reinitiating and subsequently tapering topical corticosteroids, and providing non-drug and psychological support. While HCPs felt confident in addressing concerns about topical corticosteroids and topical steroid withdrawal, approximately one-quarter (24.2%) preferred not to treat patients refusing topical corticosteroids. This study highlights variations in perception among HCPs and the need for robust research to establish clear diagnostic criteria and guidelines regarding TSW. Finally, improved awareness and open communication between HCPs and patients are essential when addressing topical steroid withdrawal.

Indexed as

Adrenal Cortex HormonesAttitude of Health PersonnelGlucocorticoidsHealth Knowledge, Attitudes, PracticeHealth PersonnelSubstance Withdrawal SyndromeWithholding TreatmentAdministration, CutaneousAdministration, TopicalAdultFemaleHealth Care SurveysHumansMaleMiddle AgedNetherlandsAdrenal Cortex HormonesGlucocorticoids

Identifiers

PMID40792577
PMCPMC12359819

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.