Evidence map›Paper›PMID 40792479›Full record

ArticleJournal of proteome research2025

Serum

Sherifdeen Onigbinde, Joy Solomon, Cristian D Gutierrez-Reyes, Oluwatosin Daramola, Mojibola Fowowe, Moyinoluwa Adeniyi, Kelly N DuBois, Kelly M Bakulski, Nicholas M Kanaan, David M Lubman and 1 more

Abstract read
In one paragraph

Article in Journal of proteome research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. PredictiveACS omega · 2026
    Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sherifdeen OnigbindeDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, Texas 79409, United States.
Joy SolomonDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, Texas 79409, United States.
Cristian D Gutierrez-ReyesDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, Texas 79409, United States.
Oluwatosin DaramolaDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, Texas 79409, United States.
Mojibola FowoweDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, Texas 79409, United States.
Moyinoluwa AdeniyiDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, Texas 79409, United States.
Kelly N DuBoisDepartment of Translational Science and Molecular Medicine, College of Human Medicine, Michigan State University, Grand Rapids, Michigan 49503, United States.
Kelly M BakulskiDepartment of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan 48103, United States.
Nicholas M KanaanDepartment of Translational Science and Molecular Medicine, College of Human Medicine, Michigan State University, Grand Rapids, Michigan 49503, United States.
David M LubmanDepartment of Surgery, The University of Michigan, Ann Arbor, Michigan 48109, United States.ORCID 0000-0001-7731-0232
Yehia MechrefDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, Texas 79409, United States.ORCID 0000-0002-6661-6073

Funding

Research Education ComponentP30AG072931 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Henry L Paulson · 2021 to 2026
$26.5M
Supplemental for Detection of Glycopeptides of MCI in Patient SerumR01CA160254 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI David M. Lubman · 2012 to 2026
$5.4M
Sensitive and Quantitative MS-bases Glycomic Mapping PlatformR01GM112490 · NIGMS · TEXAS TECH UNIVERSITY · PI MECHREF, YEHIA · 2014 to 2024
$3.2M
Quantitative Characterization of Glycopeptide IsomersR01GM130091 · NIGMS · TEXAS TECH UNIVERSITY · PI Yehia Mechref · 2019 to 2026
$2.5M
Screening of Glycan Markers in Serum for Early Detection of HCC in Different Etiologies of DiseaseU01CA225753 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LUBMAN, DAVID M., MECHREF, YEHIA · 2018 to 2021
$2.0M
NCI NIH HHS R01 CA160254NCI NIH HHS U01 CA225753NIA NIH HHS P30 AG072931NIGMS NIH HHS R01 GM112490NIGMS NIH HHS R01 GM130091
6 · The paper itself

Abstract

Alzheimer's disease (AD) is a neurodegenerative disorder marked by progressive cognitive decline, affecting millions worldwide. Early diagnosis and intervention are crucial yet challenging, particularly in distinguishing between Mild Cognitive Impairment (MCI) subtypes, which often precede AD. Recent studies have highlighted the significant role of glycosylation, specifically

Indexed as

Alzheimer DiseaseCognitive DysfunctionPolysaccharidesAgedAged, 80 and overBiomarkersChromatography, LiquidEarly DiagnosisFemaleGlycosylationHumansMaleTandem Mass SpectrometryBiomarkersPolysaccharidesAlzheimer’s diseasebiomarkersisomersLC-MS/MSmild cognitive impairmentsN-glycans

Identifiers

PMID40792479
PMCPMC12814892

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.