Evidence map›Paper›PMID 40792345›Full record

ReviewCureus2025

The Role of Platinum-Based Chemotherapy in the Pathogenesis of Tendinosis in Cancer Patients.

Joseph Bisiani, Brian Lynch

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Joseph BisianiDepartment of Orthopedics, Renaissance School of Medicine, Stony Brook University, Stony Brook, USA.
Brian LynchDepartment of Orthopedics, Renaissance School of Medicine, Stony Brook University, Stony Brook, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Currently, there are numerous anti-cancer drugs to prevent the spread of different neoplasms. Patients who depend on these medications as a form of treatment look to hopefully minimize the spread of cancer. However, there are well-known side effects of platinum-based chemotherapies, such as different electrolyte imbalances. These disturbances could possibly lead to the pathogenesis of tendinosis among cancer patients who take long-term platinum-based chemotherapy treatments, something that has not been thoroughly studied and warrants further investigation. Electrolyte disturbances in tendons can lead to dehydration, which can impair collagen synthesis and ultimately lead to tendon degeneration among cancer patients who are utilizing these long-term platinum cancer drugs.

Indexed as

cancer patientscarboplatincisplatincollagenoxaliplatinplatinum-based chemotherapytendinosistoxicity

Identifiers

PMID40792345
PMCPMC12339036

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.