Evidence map›Paper›PMID 40792231›Full record

ArticleThe journal of liquid biopsy2025

Harmonization trial on

Francesco Pepe, Gianluca Russo, Konstantinos Venetis, Claudia Scimone, Lucia Palumbo, Mariantonia Nacchio, Domenica di Giovanni, Claudia Sarracino, Ilaria Tomaiuolo, Elisabetta Zulato and 28 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The journal of liquid biopsy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. The journal of liquid biopsy · 2026
    Review
  2. Liquid biopsy in solid tumours: expert opinion paper of the European society of pathology.Virchows Archiv : an international journal of pathology · 2026
    Review
  3. Pathologica · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

38 authors.

Francesco PepeDepartment of Public Health, Federico II University of Naples, Via S. Pansini, 5, 80131, Naples, Italy.
Gianluca RussoDepartment of Public Health, Federico II University of Naples, Via S. Pansini, 5, 80131, Naples, Italy.
Konstantinos VenetisDivision of Pathology, European Institute of Oncology, IRCCS, Milan, Italy.
Claudia ScimoneDepartment of Public Health, Federico II University of Naples, Via S. Pansini, 5, 80131, Naples, Italy.
Lucia PalumboDepartment of Public Health, Federico II University of Naples, Via S. Pansini, 5, 80131, Naples, Italy.
Mariantonia NacchioDepartment of Public Health, Federico II University of Naples, Via S. Pansini, 5, 80131, Naples, Italy.
Domenica di GiovanniDepartment of Public Health, Federico II University of Naples, Via S. Pansini, 5, 80131, Naples, Italy.
Claudia SarracinoDepartment of Public Health, Federico II University of Naples, Via S. Pansini, 5, 80131, Naples, Italy.
Ilaria TomaiuoloDepartment of Public Health, Federico II University of Naples, Via S. Pansini, 5, 80131, Naples, Italy.
Elisabetta ZulatoDepartment of Pathology, Azienda Ospedale-Università Padova, Padua, Italy.
Matteo FassanDepartment of Medicine - DIMED, University of Padua, Padova, Veneto, Italy.
Daniela RighiAnatomical Pathology Operative Research Unit, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo, 200, 00128, Roma, Italy.
Giuseppe PerroneAnatomical Pathology Operative Research Unit, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo, 200, 00128, Roma, Italy.
Dario de BiaseSolid Tumor Molecular Pathology Laboratory, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Gabriele CasatiDepartment of Medicine and Surgery, Pathology, IRCCS Fondazione San Gerardo Dei Tintori, University of Milano-Bicocca, Milan, Italy.
Fabio PagniDepartment of Medicine and Surgery, Pathology, IRCCS Fondazione San Gerardo Dei Tintori, University of Milano-Bicocca, Milan, Italy.
Lucia GullottiDivision of Pathology, Humanitas Istituto Clinico Catanese, 95045, Catania, Italy.
Antonio RizzoDivision of Pathology, Humanitas Istituto Clinico Catanese, 95045, Catania, Italy.
Alessandro PerezSection of Medical Oncology, Department of Precision Medicine in Medical, Surgical and Critical Care (MEPRECC), University of Palermo, 90127, Palermo, Italy.
Antonio RussoSection of Medical Oncology, Department of Precision Medicine in Medical, Surgical and Critical Care (MEPRECC), University of Palermo, 90127, Palermo, Italy.
Katia ZavagliaDivision of Molecular Genetics, Department of Laboratory Medicine, Pisa University Hospital, Pisa, Italy.
Gianluca GragnanoDepartment of Public Health, Federico II University of Naples, Via S. Pansini, 5, 80131, Naples, Italy.
Domenico CozzolinoDepartment of Public Health, Federico II University of Naples, Via S. Pansini, 5, 80131, Naples, Italy.
Sabrina AlfanoDepartment of Public Health, Federico II University of Naples, Via S. Pansini, 5, 80131, Naples, Italy.
Cristian ScatenaDivision of Pathology, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.
Sara D'andreaMolecular Oncology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, National Cancer Institute, Aviano, PN, Italy.
Monica SchiappacassiMolecular Oncology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, National Cancer Institute, Aviano, PN, Italy.
Giuseppina RoscignoDepartment of Biology, Complesso Universitario Monte Sant'Angelo, University of Naples Federico II, Via Cintia 4, 80126, Naples, Italy.
Alessia PaganottiDepartment of Pathology, 'Maggiore della Carità' Hospital, Novara, Italy.
Renzo BoldoriniDepartment of Pathology, 'Maggiore della Carità' Hospital, Novara, Italy.
Francesco EspositoInstitute of Endotypes in Oncology, Metabolism and Immunology (IEOMI) "G. Salvatore", National Research Council (CNR), Naples, Italy.
Pierlorenzo PallanteInstitute of Endotypes in Oncology, Metabolism and Immunology (IEOMI) "G. Salvatore", National Research Council (CNR), Naples, Italy.
Daniela FurlanUnit of Pathology, Department of Medicine and Technological Innovation, University of Insubria, Varese, Italy.
Marta SbaragliaDepartment of Integrated Diagnostics, Azienda Ospedale-Università Padova, Department of Medicine, University of Padua, Italy.
Angelo Paolo Dei TosDepartment of Integrated Diagnostics, Azienda Ospedale-Università Padova, Department of Medicine, University of Padua, Italy.
Giancarlo TronconeDepartment of Public Health, Federico II University of Naples, Via S. Pansini, 5, 80131, Naples, Italy.
Nicola FuscoDepartment of Oncology and Hemato-Oncology, University of Milan, Milan, Italy.
Umberto MalapelleDepartment of Public Health, Federico II University of Naples, Via S. Pansini, 5, 80131, Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: To date, Methods: A total of 10 μl of gDNA from each reference sample built to mimic clinically detectable Results: Conclusions: NGS and dPCR systems may be considered valid technical solutions to target low frequency

Indexed as

BreastMolecular pathologyTumour biomarker

Identifiers

PMID40792231
PMCPMC12337205

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.