Evidence map›Paper›PMID 40792194›Full record

ArticleJournal of arrhythmia2025

Prevalence, Characteristics, and Arrhythmogenic Substrate of Mitral Annular Disjunction Assessed by Cardiac Magnetic Resonance Imaging in Patients With Apparently Idiopathic Ventricular Arrhythmia.

Saori Asada, Hiroshi Morita, Norihisa Toh, Takuro Masuda, Akira Ueoka, Masakazu Miyamoto, Koji Nakagawa, Nobuhiro Nishii, Kazufumi Nakamura, Shinsuke Yuasa

Abstract read
In one paragraph

Article in Journal of arrhythmia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Mitral Annular Disjunction and Coalescing Myths in Cardiology.Arrhythmia & electrophysiology review · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Saori AsadaDepartment of Cardiovascular Medicine, Dentistry and Pharmaceutical Sciences Okayama University Graduate School of Medicine and Dentistry Okayama Japan.ORCID https://orcid.org/0000-0003-0167-9871
Hiroshi MoritaDepartment of Cardiovascular Therapeutics Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Okayama Japan.ORCID https://orcid.org/0000-0001-6419-1246
Norihisa TohDepartment of Cardiovascular Medicine, Dentistry and Pharmaceutical Sciences Okayama University Graduate School of Medicine and Dentistry Okayama Japan.
Takuro MasudaDepartment of Cardiovascular Medicine, Dentistry and Pharmaceutical Sciences Okayama University Graduate School of Medicine and Dentistry Okayama Japan.
Akira UeokaDepartment of Cardiovascular Medicine, Dentistry and Pharmaceutical Sciences Okayama University Graduate School of Medicine and Dentistry Okayama Japan.
Masakazu MiyamotoDepartment of Cardiology Kagawa Prefectural Central Hospital Kagawa Japan.
Koji NakagawaDepartment of Cardiovascular Medicine, Dentistry and Pharmaceutical Sciences Okayama University Graduate School of Medicine and Dentistry Okayama Japan.
Nobuhiro NishiiDepartment of Cardiovascular Therapeutics Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Okayama Japan.ORCID https://orcid.org/0000-0003-3183-5660
Kazufumi NakamuraDepartment of Cardiovascular Medicine, Dentistry and Pharmaceutical Sciences Okayama University Graduate School of Medicine and Dentistry Okayama Japan.
Shinsuke YuasaDepartment of Cardiovascular Medicine, Dentistry and Pharmaceutical Sciences Okayama University Graduate School of Medicine and Dentistry Okayama Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Mitral annular disjunction (MAD) is linked to an increased risk of sudden cardiac death, but its association with ventricular arrhythmias (VAs) in Japanese patients is unclear. Methods: We retrospectively analyzed 129 Japanese patients with VAs and no overt structural heart disease who underwent echocardiography and cardiac MRI. Results: MAD was diagnosed in 7.0%, and in 14% of patients with VAs originating from the mitral valve apparatus. MAD was significantly associated with multifocal VAs, late gadolinium enhancement in the papillary muscles, and greater mitral regurgitation. Conclusion: MAD may be an important arrhythmogenic substrate in apparently idiopathic VAs among Japanese patients.

Indexed as

arrhythmic mitral valve prolapsesidiopathic ventricular arrhythmialate gadolinium enhancementmitral annular disjunctionmultifocal ventricular arrhythmia

Identifiers

PMID40792194
PMCPMC12336286

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.