ArticleClinical ophthalmology (Auckland, N.Z.)2025
Intense Pulsed Light Combined with Low Level Blue and Red Light Therapy for
Article in Clinical ophthalmology (Auckland, N.Z.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Intense pulsed light as a multi-target intervention paradigm for refractory ocular surface diseases: a review.Eye and vision (London, England) · 2026Review
- Home-based low-level light therapy using a commercial LED mask for dry eye disease.International ophthalmology · 2026Observational
- Pulsed photobiomodulation reprograms the tumor immune microenvironment to restore local T cell-mediated antitumor immunity.iScience · 2026Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: Patients and Methods: Medical records of patients with Results: Data from 34 eyes of 17 patients (3 males, 14 females; mean age 64.6±10.0 years) were included. A mean of 7.6 ± 3.6 treatment sessions of IPL and LLLT was performed. Mean score of collarettes decreases significantly from 1.44 ± 0.83 at T0 to 1.00 ± 0.97 at T1 (p = 0.007). The rate of eyes with saponification decreases significantly (from 41.18% to 11.76%; p = 0.002). Conjunctival hyperemia significantly decreased from 2.00 ± 0.78 to 1.47 ± 0.61 (p = 0.005). Mean CFS score decreased significantly from 0.56 ± 1.16 to 0.24 ± 0.96 (p = 0.031). Symptoms' mean score improved significantly after treatment (from 12.00 ± 5.34 to 7.76 ± 4.92; p = 0.003). No patient reported TrAEs. Conclusion: Combined light therapy with IPL and LLLT employing blue and red lights is an effective treatment strategy for patients with recalcitrant
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.