ArticleTranslational cancer research2025
Association between real-time shear wave elastography findings and HER-2 expression in breast cancer.
Article in Translational cancer research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Human epidermal growth factor receptor-2 (HER-2) overexpressing breast cancer is associated with more aggressive tumor characteristics and poorer clinical outcomes. It is important to determine HER-2 status of breast cancer for better treatment planning. This study aims to explore the correlation between real-time shear wave elastography (SWE) and HER-2 expression in breast cancer. Methods: A total of 67 patients who underwent breast cancer surgery between January 2017 and January 2021 were recruited for this retrospective study. Among 70 breast cancer lesions in the included patients, 31 lesions were HER-2 negative, and 39 lesions were HER-2 positive. SWE imaging was conducted and Young's modulus values including mean elastic modulus (E Results: The HER-2 positive group had a higher proportion of lesions with a diameter of ≥20 mm. The E Conclusions: E
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