Evidence map›Paper›PMID 40792150›Full record

ArticleTranslational cancer research2025

Construction and validation of an EGFR-related risk signature identified

Hanqin Cao, Bohao Sun, Jing Wang, Shanshan Wu, Na Shi, Jing Zhang, Yichen Wu, Hao Wang

Abstract read
In one paragraph

Article in Translational cancer research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hanqin Cao *Department of Laboratory Medicine, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Bohao Sun *Department of Pathology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Jing WangState Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, National Medical Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Shanshan WuState Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, National Medical Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Na ShiMedical Laboratory, Second Sanatorium of Air Force Healthcare Center for Special Services Hangzhou, Hangzhou, China.
Jing ZhangDepartment of Pathology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Yichen WuDepartment of Pathology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Hao WangDepartment of Clinical Laboratory, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Lung adenocarcinoma (LUAD) is a significant subtype of lung cancer, contributing to high mortality rates and posing substantial challenges to public health. This study aims to explore the significance of the epidermal growth factor receptor (EGFR)-related gene Methods: Patient RNA sequencing (RNA-seq) and clinical data were acquired from The Cancer Genome Atlas (TCGA) database. Using the least absolute shrinkage and selection operator (LASSO) Cox regression, we then generated a multigene signature of EGFR signaling-related genes (ESRGs) for the prognostic prediction of LUAD. We investigated the relationship between Results: Univariate Cox regression analysis identified that increased expression of Conclusions: These findings suggest that

Indexed as

bioinformaticsepidermal growth factor receptor (EGFR)Lung adenocarcinoma (LUAD)prognosisSHC1

Identifiers

PMID40792150
PMCPMC12335678

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.