Evidence map›Paper›PMID 40792054›Full record

ArticleFrontiers in veterinary science2025

Yeast peptides alleviate diarrhea in neonatal lambs by enhancing the colonic barrier function and modulating colonic microbiota.

Dingkun Fan, Rui Zong, Chengrui Zhang, Jixian Zhang, Jianmin Chai, Kai Cui, Naifeng Zhang

Abstract read
In one paragraph

Article in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. The potential of yeast culture for alleviating enterotoxigenicAnimal nutrition (Zhongguo xu mu shou yi xue hui) · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dingkun FanKey Laboratory of Feed Biotechnology of the Ministry of Agriculture and Rural Affairs, Institute of Feed Research of Chinese Academy of Agricultural Sciences, Beijing, China.
Rui ZongKey Laboratory of Feed Biotechnology of the Ministry of Agriculture and Rural Affairs, Institute of Feed Research of Chinese Academy of Agricultural Sciences, Beijing, China.
Chengrui ZhangKey Laboratory of Feed Biotechnology of the Ministry of Agriculture and Rural Affairs, Institute of Feed Research of Chinese Academy of Agricultural Sciences, Beijing, China.
Jixian ZhangKey Laboratory of Feed Biotechnology of the Ministry of Agriculture and Rural Affairs, Institute of Feed Research of Chinese Academy of Agricultural Sciences, Beijing, China.
Jianmin ChaiKey Laboratory of Feed Biotechnology of the Ministry of Agriculture and Rural Affairs, Institute of Feed Research of Chinese Academy of Agricultural Sciences, Beijing, China.
Kai CuiKey Laboratory of Feed Biotechnology of the Ministry of Agriculture and Rural Affairs, Institute of Feed Research of Chinese Academy of Agricultural Sciences, Beijing, China.
Naifeng ZhangKey Laboratory of Feed Biotechnology of the Ministry of Agriculture and Rural Affairs, Institute of Feed Research of Chinese Academy of Agricultural Sciences, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The underdeveloped intestinal tissue and immature microbiota in neonatal lambs predispose to frequent diarrhea or even death, expanding the breeding losses. Yeast peptides are enzymatic products of yeast strains, recognized as antimicrobial peptides due to their demonstrated antimicrobial properties. This study aimed to investigate the impacts of yeast peptides supplementation on the incidence of diarrhea in neonatal lambs, as well as the underlying regulatory mechanisms involved. Thirty-two one-day-old lambs were randomly allocated to four treatments: CON, YP500, YP1000, and YP2000, receiving 0 mg/d, 500 mg/d, 1,000 mg/d, and 2,000 mg/d of yeast peptides, respectively. The dietary supplementation of yeast peptides elicited a significant reduction in fecal scores and the incidence of diarrhea (

Indexed as

barrier functioninflammationlambsmicrobiotayeast peptides

Identifiers

PMID40792054
PMCPMC12337279

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.