Evidence map›Paper›PMID 40792045›Full record

ArticleFood science & nutrition2025

The Effect of Boron Supplementation on Kidney Stones in Patients With Nephrolithiasis: A Double-Blind Randomized Controlled Trial.

Gita Vousoughi, Hamid Soleimanzadeh, Nima Radkhah, Mohammad Asghari Jafarabadi, Fatemeh Bahri, Alireza Ostadrahimi, Vahideh Ebrahimzadeh Attari

Abstract read
In one paragraph

Article in Food science & nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gita VousoughiStudent Research Committee, Tabriz University of Medical Sciences Tabriz Iran.
Hamid SoleimanzadehNutrition Research Center Tabriz University of Medical Sciences Tabriz Iran.
Nima RadkhahStudent Research Committee, Tabriz University of Medical Sciences Tabriz Iran.ORCID https://orcid.org/0000-0002-9353-8066
Mohammad Asghari JafarabadiCabrini Research Cabrini Health Malvern Victoria Australia.
Fatemeh BahriStudent Research Committee, Tabriz University of Medical Sciences Tabriz Iran.
Alireza OstadrahimiNutrition Research Center Tabriz University of Medical Sciences Tabriz Iran.
Vahideh Ebrahimzadeh AttariDepartment of Biochemistry and Nutrition School of Nutrition and Food Sciences, Tabriz University of Medical Sciences Tabriz Iran.ORCID https://orcid.org/0000-0002-7017-2129

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kidney stones (nephrolithiasis) are a common and costly medical condition frequently linked with metabolic disorders. These disorders elevate the risk of serious complications and often necessitate invasive, expensive treatments, highlighting the need for alternative therapies. This study aimed to evaluate the effects of boron supplementation-in the form of boric acid and boron citrate-on kidney stone size and number in patients with nephrolithiasis. In this double-blind, randomized, placebo-controlled clinical trial, 60 eligible patients aged 20-65 years with nephrolithiasis were enrolled. Participants were randomly assigned to receive daily oral supplements for 8 weeks: boric acid (10 mg), boron citrate (10 mg), or placebo. The primary outcomes were kidney stone size and number; secondary outcomes included paraclinical parameters. Boron supplementation with either boric acid or boron citrate did not significantly reduce the number of kidney stones in fully adjusted models compared to the control group. The incidence rate ratios (IRR) were 1.09 (95% CI: 0.65-1.85;

Indexed as

boronkidney stonesnephrolithiasisrandomized controlled trial

Identifiers

PMID40792045
PMCPMC12336847

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.