Evidence map›Paper›PMID 40791870›Full record

ReviewJournal of pain research2025

Efficacy of Cognitive Behavioral Therapy for Kinesiophobia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Shuyi Zhu, Yanxin Xu, Lin Wang, Jing Chen, Aoxiang Luo

Abstract readReview
In one paragraph

Review in Journal of pain research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shuyi ZhuSchool of Nursing, Guangdong Pharmaceutical University, Guangzhou, Guangdong, 510310, People's Republic of China.ORCID 0009-0008-2096-3994
Yanxin XuSchool of Nursing, Guangdong Pharmaceutical University, Guangzhou, Guangdong, 510310, People's Republic of China.
Lin WangDepartment of Spinal Orthopedics, Guangdong Second Provincial General Hospital, Guangzhou, Guangdong, 510317, People's Republic of China.
Jing ChenSchool of Nursing, Guangdong Pharmaceutical University, Guangzhou, Guangdong, 510310, People's Republic of China.
Aoxiang LuoSchool of Nursing, Guangdong Pharmaceutical University, Guangzhou, Guangdong, 510310, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Kinesiophobia presents a significant barrier to rehabilitation across multiple conditions. While cognitive behavioral therapy (CBT) holds potential for addressing phobic responses, its specific efficacy against kinesiophobia requires clarification. Purpose: To systematically evaluate CBT's efficacy in reducing kinesiophobia among adults. Methods: Following Cochrane guidelines, two independent reviewers searched six international databases (PubMed, Cochrane Library, Embase, EBSCO, Web of Science, Scopus) and four Chinese databases (SinoMed, CNKI, VIP, WanFang) for randomized controlled trials (RCTs) on CBT interventions targeting kinesiophobia, from inception through November 2024. Independent dual review was conducted for study selection, data extraction, and quality assessment (Cochrane Risk of Bias tool). Random-effects meta-analyses were performed using RevMan 5.4 and Stata 12, with heterogeneity quantified by I² statistics. Results: Eight trials with 938 participants were included. CBT demonstrated significantly greater reduction in kinesiophobia scores versus controls (MD=-5.67, [95% CI:-6.99, -4.35], Conclusion: This meta-analysis provides robust evidence that CBT effectively reduces kinesiophobia, particularly as monotherapy for lumbar conditions with sustained follow-up. Clinicians should prioritize CBT implementation to enhance recovery. While results are compelling, confirmatory trials with rigorous methodology and adequate power are warranted.

Indexed as

cognitive behavioral therapykinesiophobiameta-analysisrandomized controlled trials

Identifiers

PMID40791870
PMCPMC12336382

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.