Evidence map›Paper›PMID 40791856›Full record

ArticleFrontiers in bioengineering and biotechnology2025

Awareness of the dual-use dilemma in scientific research: reflections and challenges to Latin America.

Jose Alonso Flores-Coronado, Alondra Yamileth Alanis-Valdez, Maria Fernanda Herrera-Saldivar, Aldo Sebastian Flores-Flores, Jose Manuel Vazquez-Guillen, Reyes S Tamez-Guerra, Cristina Rodriguez-Padilla

Abstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jose Alonso Flores-CoronadoUniversidad Autónoma de Nuevo León, Facultad de Ciencias Biológicas, Laboratorio de Inmunología y Virología, San Nicolás de los Garza, Nuevo León, Mexico.
Alondra Yamileth Alanis-ValdezUniversidad Autónoma de Nuevo León, Facultad de Ciencias Biológicas, Laboratorio de Inmunología y Virología, San Nicolás de los Garza, Nuevo León, Mexico.
Maria Fernanda Herrera-SaldivarUniversidad Autónoma de Nuevo León, Facultad de Ciencias Biológicas, Laboratorio de Inmunología y Virología, San Nicolás de los Garza, Nuevo León, Mexico.
Aldo Sebastian Flores-FloresUniversidad Autónoma de Nuevo León, Facultad de Ciencias Biológicas, Laboratorio de Inmunología y Virología, San Nicolás de los Garza, Nuevo León, Mexico.
Jose Manuel Vazquez-GuillenUniversidad Autónoma de Nuevo León, Facultad de Ciencias Biológicas, Laboratorio de Inmunología y Virología, San Nicolás de los Garza, Nuevo León, Mexico.
Reyes S Tamez-GuerraUniversidad Autónoma de Nuevo León, Facultad de Ciencias Biológicas, Laboratorio de Inmunología y Virología, San Nicolás de los Garza, Nuevo León, Mexico.
Cristina Rodriguez-PadillaUniversidad Autónoma de Nuevo León, Facultad de Ciencias Biológicas, Laboratorio de Inmunología y Virología, San Nicolás de los Garza, Nuevo León, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The dual-use dilemma compels us to reflect on scientific responsibility, ethical regulation, and the role of society in the governance of knowledge. While science has the potential to transform the world for the better, it can also become a double-edged sword if the implications of its potential misuse are overlooked. This is particularly relevant in the life sciences, where advances can be repurposed for harmful by secondary actors. Addressing this challenge requires the development of preventive tools, biosafety and biosecurity measures specifically designed for dual-use research, and clear, up-to-date regulatory frameworks at both national and international levels. These mechanisms should aim to anticipate risks, restrict unauthorized access to sensitive information, and foster a culture of responsibility within the scientific community, without hindering the advancement of knowledge or obstructing legitimate innovation. This perspective explores the dual-use dilemma through a global lens, with a specific focus on Latin America, a region where policies and institutional awareness on dual-use risks remain limited. By analyzing illustrative case studies, existing international tools, and regional gaps, this work highlights both the obstacles and opportunities for strengthening dual-use governance in Latin American research systems.

Indexed as

biosafetybiosecuritydual-use researchethics researchrisk assessment

Identifiers

PMID40791856
PMCPMC12336261

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.