Evidence map›Paper›PMID 40791671›Full record

ArticlemedRxiv : the preprint server for health sciences2025

Svitlana V Bach, Giovanna Punzi, Nuri E Smith, Sreya Mukherjee, Joo Heon Shin, Qiang Chen, Geo Pertea, Leonardo Collado-Torres, Kristen R Maynard, Stephanie C Page and 5 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

Svitlana V BachLieber Institute for Brain Development, Johns Hopkins University Medical Campus, Baltimore (MD), USA.
Giovanna PunziLieber Institute for Brain Development, Johns Hopkins University Medical Campus, Baltimore (MD), USA.
Nuri E SmithLieber Institute for Brain Development, Johns Hopkins University Medical Campus, Baltimore (MD), USA.
Sreya MukherjeeLieber Institute for Brain Development, Johns Hopkins University Medical Campus, Baltimore (MD), USA.
Joo Heon ShinLieber Institute for Brain Development, Johns Hopkins University Medical Campus, Baltimore (MD), USA.
Qiang ChenStem Cell Translation Laboratory (SCTL), Division of Preclinical Innovation, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH), Rockville (MD), USA.
Geo PerteaLieber Institute for Brain Development, Johns Hopkins University Medical Campus, Baltimore (MD), USA.
Leonardo Collado-TorresLieber Institute for Brain Development, Johns Hopkins University Medical Campus, Baltimore (MD), USA.
Kristen R MaynardLieber Institute for Brain Development, Johns Hopkins University Medical Campus, Baltimore (MD), USA.
Stephanie C PageLieber Institute for Brain Development, Johns Hopkins University Medical Campus, Baltimore (MD), USA.
Joel E KleinmanLieber Institute for Brain Development, Johns Hopkins University Medical Campus, Baltimore (MD), USA.
Thomas M HydeLieber Institute for Brain Development, Johns Hopkins University Medical Campus, Baltimore (MD), USA.
Daniel R WeinbergerLieber Institute for Brain Development, Johns Hopkins University Medical Campus, Baltimore (MD), USA.
Keri MartinowichLieber Institute for Brain Development, Johns Hopkins University Medical Campus, Baltimore (MD), USA.ORCID 0000-0002-5237-0789
Gianluca UrsiniLieber Institute for Brain Development, Johns Hopkins University Medical Campus, Baltimore (MD), USA.ORCID 0000-0002-4733-5196

Funding

Regulation of neural activity in fear circuits by promoter IV derived BDNFR01MH105592 · NIMH · LIEBER INSTITUTE, INC. · PI MARTINOWICH, KERI · 2015 to 2024
$5.6M
Comprehensive Human Expressed Sequences in Brain (CHESS-BRAIN) and their roles in neuropsychiatric illnessR01MH123567 · NIMH · JOHNS HOPKINS UNIVERSITY · PI SALZBERG, STEVEN L. · 2021 to 2025
$2.8M
NIMH NIH HHS R01 MH105592NIMH NIH HHS R01 MH123567
6 · The paper itself

Abstract

Divergent transcription from bidirectional promoters is frequently observed in eukaryotic genomes, but the biological relevance of divergent RNA transcripts (DT) is unknown. We identified and characterized

Identifiers

PMID40791671
PMCPMC12338882

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.