Evidence map›Paper›PMID 40791579›Full record

ArticleBJUI compass2025

Long-term outcomes in patients with intracorporeal robot-assisted pyramid neobladder.

Elizabeth Day, Pratham Upadhyay, Raashi Padhiyar, Lazaros Tzelves, Bernadett Szabados, Anthony Ta, Ashwin Sridhar, John Kelly

Abstract read
In one paragraph

Article in BJUI compass, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Elizabeth DayDepartment of Urology University College London Hospital London UK.
Pratham UpadhyayMedical School University College London London UK.ORCID https://orcid.org/0009-0007-9579-6951
Raashi PadhiyarMedical School University College London London UK.
Lazaros Tzelves2nd Department of Urology, Sismanogleio Hospital National and Kapodistrian University of Athens Greece.ORCID https://orcid.org/0000-0003-4619-9783
Bernadett SzabadosDepartment of Urology University College London Hospital London UK.
Anthony TaDepartment of Urology St Vincent Hospital Melbourne Australia.
Ashwin SridharDepartment of Urology University College London Hospital London UK.ORCID https://orcid.org/0000-0001-8070-4822
John KellyDepartment of Urology University College London Hospital London UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: A range of techniques have been described for robotic-assisted intracorporeal neobladder construction. The pyramid neobladder has now been performed for over 10 years. We now describe the long-term outcomes, including the impact of function preservation through nerve and prostate capsule sparing in the male population. Subjects/Patients and Methods: All patients who underwent pyramid neobladder construction between January 2015 and December 2023 at the University College London Hospital (UK) were reviewed. Patients were selected for function preservation based on baseline sexual function/wishes, PSA ± multiparametric prostate MRI. Selected oncological, functional and patient reported outcomes were assessed. Results: A total of 71 patients were included; 87% (61/71) were men. About 65% (40/61) underwent either nerve- or prostate capsule-sparing surgery. Median follow-up was 57.8 months (IQR 48.3). In male patients, there was no difference between the 12- and 24-month cancer specific and overall survival rates between the function sparing groups. There were no positive prostate cancer margins. Daytime continence was 75% (39/52) and 67% (6/9), and nighttime was 17% (9/52) and 11% (1/9), in men and women, respectively. There was no significant difference between the male function sparing groups ( Conclusion: Sexual function had the largest impact on quality of life and may be improved with function-sparing techniques. The burden of additional complications including neobladder rupture and urinary tract infections was also highlighted.

Indexed as

bladder cancerneobladderreconstructive urologyrobotic cystectomyurinary diversion

Identifiers

PMID40791579
PMCPMC12339043

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.