Evidence map›Paper›PMID 40791430›Full record

ArticlebioRxiv : the preprint server for biology2025

Adaptive

Savana Hadjipanteli, Natalie Copeland, Nancy Marmolejo Bustamante, Maureen Nweke, Basabdatta Adhikari, Erin S Kelleher

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Savana HadjipanteliDepartment of Biology and Biochemistry, University of Houston, Houston, TX 77204.
Natalie CopelandDepartment of Biology and Biochemistry, University of Houston, Houston, TX 77204.
Nancy Marmolejo BustamanteDepartment of Biology and Biochemistry, University of Houston, Houston, TX 77204.
Maureen NwekeDepartment of Biology and Biochemistry, University of Houston, Houston, TX 77204.
Basabdatta AdhikariDepartment of Biology and Biochemistry, University of Houston, Houston, TX 77204.
Erin S KelleherDepartment of Biology and Biochemistry, University of Houston, Houston, TX 77204.ORCID 0000-0002-1827-067X

Funding

Mechanisms and Evolution of Host Tolerance to Transposable ElementsR35GM138112 · NIGMS · UNIVERSITY OF HOUSTON · PI KELLEHER, ERIN S · 2020 to 2024
$1.8M
NIGMS NIH HHS R35 GM138112
6 · The paper itself

Abstract

Transposable elements are genetic parasites whose mobilization throughout the genome is a major source of deleterious mutations. However, some TE insertions are beneficial because they improve host fitness. Adaptive TE insertions sometimes alter the function of adjacent genes by positively and negatively impacting their expression, or by altering their encoding proteins. Alternatively, individual TE insertions can also be adaptive because they occur in piRNA clusters and lead to piRNA-mediated silencing of transposition. In a recent laboratory evolution experiment, we discovered that the long non-coding RNA

Identifiers

PMID40791430
PMCPMC12338743

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.