ArticleFrontiers in nutrition2025
Global, regional, and national anemia burden among women of reproductive age (15-49 years) from 1990 to 2021: an analysis of the Global Burden of Disease Study 2021.
Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association between anaemia and osteoporosis: a systematic review and meta-analysis.Annals of medicine · 2026Pooled it
- Review of the influence of anaemia on the effect of total hip arthroplasty, and the prognosis of patients: recent advances and future directions.Annals of medicine · 2026Review
- Clinical care and research gaps in iron deficiency.Blood advances · 2026Article
- Depressive symptom profiles across pregnant, postpartum, and nonperipartum women: measurement invariance and differential item functioning analyses of 2005-2021 NHANES data.BMC public health · 2026Article
- Adherence, safety, bioavailability, and acceptability of amaranth grain flatbread during pregnancy: evidence from a cluster randomized trial in Sidama region, Ethiopia.BMC nutrition · 2026Article
- Article
- An Updated Review on Iron Deficiency Anemia: From Epidemiology to Diagnosis, Etiology, Prevention and Treatment.Journal of blood medicine · 2026Review
- Burden of disease attributable to tobacco, high alcohol use, and drug use from 1990 to 2021.Frontiers in nutrition · 2026Article
- Global burden of anemia attributed to chronic kidney disease: prevalence, years lived with disability, and predictions to 2035 (Global burden of disease 2021).Frontiers in nutrition · 2025Article
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6 authors.
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Abstract
Background: Anemia remains a significant global health challenge, disproportionately affecting women of reproductive age (WRA, 15 to 49 years) due to physiological and socioeconomic factors. However, there is a lack of high-quality data on anemia burden and causes analysis in this population. The aim of this study is to provide a comprehensive global assessment of anemia burden and its underlying causes among WRA. Methods: Using data from the Global Burden of Disease Study (GBD) 2021, we evaluated the prevalence, years lived with disability (YLDs), and underlying causes of anemia among WRA at global, regional, and national levels. We also evaluated the association between anemia burden and the socio-demographic index (SDI), quantified temporal trends of anemia burden from 1990 to 2021, and projected future burden to 2030. Results: Globally in 2021, there were 657.09 million (95% uncertainty interval [UI]: 643.59 to 671.22) anemia cases and 18.07 million (95% UI: 12.00 to 26.17) YLDs among WRA. The global age-standardized prevalence rates (ASPR) and YLDs rates per 100,000 were 33,716.77 (95% UI: 33,023.84 to 34,441.71) and 927.03 (95% UI: 615.40 to 1,342.99) in 2021, and they decreased by 0.181% and 0.539% annually from 1990 to 2021, respectively. However, the decline in ASPR stagnated after 2009, with a slight increase observed through 2021, primarily driven by rising mild anemia. An inverse relationship existed between SDI and anemia burden across regions and nations. The most common causes of anemia were dietary iron deficiency, hemoglobinopathies and hemolytic anemias, and other neglected tropical diseases, with HIV/AIDS and malaria being most prominent in specific regions. Projections indicate anemia cases and YLD counts will rise consistently from 2022 to 2030, while ASPR and age-standardized YLD rates will decline. Conclusion: Anemia among WRA is a major public health burden worldwide with persistent regional and socioeconomic disparities. Mitigating this burden requires continued efforts addressing underlying causes, reducing socioeconomic inequities, and improving access to healthcare and nutritional interventions.
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