Evidence map›Paper›PMID 40791224›Full record

ArticleComputational and structural biotechnology journal2025

Decoding PDI diversity: Insights into structure, domains, and functionality in sorghum.

Carla F López-Gómez, Marc T Morris, Karen Massel, Millicent Smith, Peter Crisp, Gerhard Schenk, Ian D Godwin

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In one paragraph

Article in Computational and structural biotechnology journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Carla F López-GómezQueensland Alliance for Agriculture and Food Innovation, The University of Queensland, Brisbane, QLD, Australia.
Marc T MorrisSchool of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, QLD, Australia.
Karen MasselQueensland Alliance for Agriculture and Food Innovation, The University of Queensland, Brisbane, QLD, Australia.
Millicent SmithSchool of Agriculture and Food Sustainability, The University of Queensland, Brisbane, QLD, Australia.
Peter CrispSchool of Agriculture and Food Sustainability, The University of Queensland, Brisbane, QLD, Australia.
Gerhard SchenkSchool of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, QLD, Australia.
Ian D GodwinQueensland Alliance for Agriculture and Food Innovation, The University of Queensland, Brisbane, QLD, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Proteins play indispensable roles in cellular function, acting as both structural components and catalysts for essential biological processes. Their proper folding into three-dimensional structures is critical for functionality. To ensure correct folding, proteins interact with chaperones and folding catalysts such as Protein Disulfide Isomerases (PDIs), which assist in the formation and rearrangement of disulfide bonds that stabilize proteins by linking cysteine residues. PDIs are part of the thioredoxin (TRX) superfamily and are characterized by a conserved CXXC motif that contributes to their redox potential. They exhibit isomerase and oxidoreductase activities, that enable them to rearrange and form new disulfide bonds. PDI family members in sorghum (SbPDI) present a broad and largely unexplored diversity in domain order, structure, and architecture between or even within species. To shed light on this diversity, we identified and characterized PDI family members in sorghum

Indexed as

ChaperonesConformational dynamicsProtein disulfide isomerasesProtein foldingThioredoxin superfamily

Identifiers

PMID40791224
PMCPMC12337123

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.