ArticleFrontiers in psychiatry2025
A U-shaped relationship between nighttime sleep duration and new-onset emotional, nervous, or psychiatric problems: a prospective cohort study from China.
Article in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: Sleep plays an important role in maintaining physical and mental health, and it is important to study the relationship between sleep duration and new-onset emotional, nervous, or psychiatric problems (ENP). Methods: A prospective cohort study was performed based on data from Wave 2011, 2013,2015 and 2018 in the China Health and Retirement Longitudinal Study (CHARLS) databases. Sleep duration was assessed by self-reported nighttime sleep and daytime nap duration. Self-reported diagnoses were used to identify the new-onset emotional, nervous, or psychiatric problems (ENP). We used different logistic regression models to explore the potential effects of sleep duration on ENP and performed mediation analyses to assess the mediating roles of BMI, hypertension, and diabetes(DM). Results: Among 10,225 participants, 221 (2.16%) developed ENP during follow-up. The mean nighttime sleep duration was significantly shorter in the ENP group than in the non-ENP group. A restricted cubic spline regression model revealed a U-shaped relationship between nighttime sleep duration and ENP risk, with the lowest risk at 6.5 hours. Mediation analyses showed that BMI, hypertension, and diabetes did not significantly mediate this association (P values for ACME were all greater than 0.05). Conclusion: A U-shaped association was observed between nighttime sleep duration and new-onset ENP, suggesting that both insufficient and excessive sleep may increase the risk of ENP. These findings highlight the importance of maintaining an optimal sleep duration for mental well-being.
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